PMID: 16512691Mar 4, 2006Paper

Treatment of adult tracheobronchomalacia and excessive dynamic airway collapse : an update

Treatments in Respiratory Medicine
Septimiu D Murgu, Henri G Colt

Abstract

Tracheobronchomalacia (TBM) and excessive dynamic airway collapse (EDAC) are both dynamic forms of central airway obstruction characterized by a decrease of >/=50% in the cross-sectional area of the tracheobronchial lumen. The differences between these two entities, however, are not uniformly accepted in the medical community. While TBM is characterized by a weakness of the tracheobronchial cartilaginous structures, EDAC is marked by excessive bulging of the posterior membrane into the airway lumen during exhalation. These disease entities are probably underdiagnosed because they present with a variety of nonspecific symptoms similar to patients with other obstructive ventilatory disorders such as asthma and COPD. Diagnosis is confirmed by dynamic radiologic imaging studies or bronchoscopy. Current therapeutic management depends on the extent, type, and severity of airway abnormalities noted and the clinical presentation. Proposed management alternatives include conservative medical therapy, and minimally invasive and open surgical interventions. Inhaled bronchodilators should be used only if symptoms and ventilatory function improve after use. Continuous positive airway pressure acts as a pneumatic stent and should be consider...Continue Reading

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References

Jan 1, 1976·Respiration; International Review of Thoracic Diseases·M Reinert, F Steurich
Feb 1, 1996·Thorax·P CollardC Francis
Feb 26, 1999·Archives of Otolaryngology--head & Neck Surgery·R H FurmanL D Holinger
Aug 3, 1999·American Journal of Respiratory and Critical Care Medicine·M NoppenW Vincken
Jun 27, 2000·Respiration; International Review of Thoracic Diseases·Y TsunezukaH Shimizu
May 21, 2003·Chest Surgery Clinics of North America·Cameron D Wright

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Citations

Jun 15, 2006·Respirology : Official Journal of the Asian Pacific Society of Respirology·Septimiu D Murgu, Henri G Colt
May 23, 2008·Journal of Biomechanics·Zhongzhao TengManuel Doblare
Jun 14, 2013·Case Reports in Medicine·Sawad Boonpiyathad, Atik Sangasapaviliya
Jun 23, 2016·Annals of the American Thoracic Society·Daniel J WeinsteinMichael J Morris
Nov 27, 2007·The Annals of Thoracic Surgery·Septimiu D Murgu, Henri G Colt
Jun 20, 2018·Current Opinion in Supportive and Palliative Care·Rebecca F D'CruzNicholas Hart
Oct 29, 2015·Tuberculosis and Respiratory Diseases·Jisoo ParkYoung-Jae Cho
Jun 18, 2009·Current Opinion in Pulmonary Medicine·Chitra Kandaswamy, Vijay Balasubramanian
May 19, 2010·Expert Review of Respiratory Medicine·Ian Brent Masters, Anne Bernadette Chang
Jun 3, 2011·Critical Care Nurse·Septimiu D MurguHenri G Colt
Aug 8, 2021·Journal of Clinical Medicine·Chaitanya GadepalliAndrew Bentley
Aug 13, 2021·ERJ Open Research·Alexandros MitropoulosJames H Hull
Jan 13, 2009·Pediatric Clinics of North America·Ian Brent Masters

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