PMID: 6159063Nov 15, 1980Paper

Treatment of advanced cervical cancer by combination of bleomycin and mitomycin-C

Cancer
H B KrebsH E Averette

Abstract

A combination of bleomycin and mitomycin-C, reported as extraordinarily effective in a previous clinical trial, was used to treat 20 patients with advanced cervical cancer. Seven partial remissions (35%) and one complete remission (5%) were observed. Six of the partial remissions were of short duration (less than four months); the only patient with complete remission was still alive without evidence of disease ten months after initiation of chemotherapy. Nonresponders had a mean survival time of 6.6 months and responders 8.0 months. The treatment results confirm some efficacy of the drug regimen, although in our hands it did not live up to the high expectations raised by others.

References

Feb 1, 1976·Cancer·J F ConroyR Nuss
Nov 1, 1961·Clinical Pharmacology and Therapeutics·D A KARNOFSKY

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Citations

Jul 1, 1985·British Journal of Obstetrics and Gynaecology·C A MeanwellF G Lawton
Mar 10, 2001·Cancer Treatment Reviews·W T Bradner
Jul 10, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Harry J Long
Oct 15, 1987·Cancer·T ThigpenR McGehee
Nov 15, 1982·Cancer·B Sorbe, B Frankendal
Dec 1, 1982·Asia-Oceania Journal of Obstetrics and Gynaecology·T SugawaK Yamamoto

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