Nov 1, 1976

Treatment of angina pectoris. Pharmacologic approaches

Postgraduate Medicine
W S Aronow


The short-acting nitrite sublingual nitroglycerin is the cornerstone of drug treatment of angina pectoris. It is most useful when given two to three minutes before activity that may precipitate an anginal attack. If disabling angina persists despite medical management and there is no contraindication, the beta-adrenergic blocking agent propranolol should be tried before coronary artery surgery is considered. Newer bera-adrenergic blocking agents do not appear to be more effective than propranolol. Digitalis may be beneficial in patients with congestive heart failure or with cardiac arrhythmias responsive to digitalis and in some patients with radiographic evidence of left ventricular enlargement or with nocturnal angina resulting from increased left ventricular end-diastolic volume. If bypass graft surgery is done, medical management must be continued postoperatively.

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Mentioned in this Paper

Intravenous Injections
Ventricular Dysfunction, Left
Digitalis preparation
Entire Coronary Artery
Anginal Attack
Digitalis Glycosides
Angina Pectoris
Nitrite Measurement
Genus: Digitalis
Left Ventricular Hypertrophy

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