Treatment of angiofibromas with a scanning carbon dioxide laser: a clinicopathologic study with long-term follow-up

Journal of the American Academy of Dermatology
R C BittencourtR J Barlow

Abstract

Facial angiofibromas in tuberous sclerosis have been managed with various treatment modalities, including carbon dioxide (CO(2)) laser resurfacing. Our purpose was to perform a long-term clinicopathologic assessment of CO(2) laser treatment of angiofibromas. This was a retrospective case review of 10 patients treated with a scanning CO(2) laser to flatten lesions. Baseline clinical photographs and those taken at 6, 12, and 24 months after the operation were assessed by a blinded observer. Patients also evaluated outcomes. Biopsy specimens taken immediately and at 4 months after the operation were reviewed. Three groups of patients were identified: the first comprised 2 patients with sustained excellent and good outcomes. A second group (3 patients) had excellent outcomes in the early and medium term but then demonstrated partial deterioration. The last group (5 patients) had a range of early results with invariably poor outcomes at 24 months. In contrast, patients' self-assessment at 24 months was good or excellent in 8 of 10 cases. All biopsy specimens taken immediately after the procedure demonstrated ablation extending into the papillary dermis. Residual angiofibromas were present in 6 biopsy specimens. At 4 months, all biop...Continue Reading

Citations

Jan 30, 2008·BMC Dermatology·Aubrey RauktysSandra L Dabora
Aug 8, 2002·Journal of Clinical Laser Medicine & Surgery
Jul 20, 2007·Journal of the American Academy of Dermatology·Robert A SchwartzSergiusz Jóźwiak
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Sep 25, 2004·Journal of the American Academy of Dermatology·Eleni PapakonstantinouGeorge Karakiulakis
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Mar 8, 2014·International Journal of Dermatology·Gang MaYunbo Jin
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