PMID: 7008801Jan 1, 1981Paper

Treatment of Behcet's syndrome with levamisole

Arthritis and Rheumatism
P de MerieuxH E Paulus

Abstract

The clinical response to levamisole in 11 patients with complete Behcet's syndrome was reviewed. Nine patients responded, 3 completely and 6 partially, with reduction in the number and severity of buccal and genital lesions. In 3 patients each, ocular inflammation and gastrointestinal involvement responded to levamisole, and in 1 patient neurologic status improved. Levamisole was purposely discontinued in 3 patients to assess its true role in disease control. Each patient experienced a flare. Reintroduction of therapy controlled the flare in all cases, although 1 patient subsequently relapsed while continuing therapy. Two patients failed to respond. Side effects necessitated permanent discontinuation of the drug in 2 respondent patients, but in no case did neutropenia or agranulocytosis develop. These preliminary results suggest that levamisole may be useful in the therapy of the various manifestations of Behcet's syndrome and that a controlled prospective study is indicated.

References

Jun 1, 1979·The American Journal of Medicine·C N GambleW J Boyer
Mar 12, 1977·British Medical Journal·J D MeyerW Peremans
May 28, 1977·British Medical Journal·B D Williams, T Lehner
May 1, 1979·Seminars in Arthritis and Rheumatism·T ShimizuK Hayashi
Oct 13, 1973·Lancet·H VerhaegenJ Brugmans
May 1, 1969·The Journal of Allergy·C E Buckley, J P Gills
Dec 7, 1974·British Medical Journal·J Symoens, J Brugmans
Sep 1, 1973·The British Journal of Ophthalmology·M I Abdalla, N el-D Bahoat
May 1, 1969·Archives of Ophthalmology·V G Wong
Oct 1, 1971·Annals of Internal Medicine·J D O'DuffyS Deodhar
Oct 1, 1970·Archives of Ophthalmology·J G Mamo, S A Azzam
Jan 1, 1968·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·E RosseletG Zenklusen
Mar 1, 1969·Annals of the Rheumatic Diseases·R M Mason, C G Barnes
Feb 25, 1967·British Medical Journal·T Lehner

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Citations

Sep 1, 1986·Clinical Rheumatology·M H Hamza
Apr 28, 2004·American Journal of Clinical Dermatology·Noah ScheinfeldJeffrey M Weinberg
Dec 7, 2006·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Pin Lin, George Liang
Sep 1, 1986·The British Journal of Dermatology·C G RanselaarH C Kluin-Nelemans
Apr 1, 1984·The British Journal of Dermatology·K E Sharquie
Nov 1, 1982·International Journal of Dermatology·R M Harper, B S Allen
Jun 1, 1982·Arthritis and Rheumatism·M HamzaH Ben Ayed
Jan 1, 1984·The American Journal of Medicine·J D O'DuffyN P Goldstein
Aug 16, 2016·Clinical Reviews in Allergy & Immunology·Cecilia Beatrice ChighizolaPier Luigi Meroni
Mar 26, 2011·Anais Brasileiros De Dermatologia·Renan Rangel BonamigoGislaine Silveira Olm
Mar 14, 2007·Annals of Vascular Surgery·Ufuk AlpagutEnver Dayioglu
Jan 1, 1991·International Journal of Dermatology·H SimsekH Telatar
Jul 1, 1982·Arthritis and Rheumatism·M Mannik
Jan 1, 1984·International Journal of Dermatology·R C WongL A Diaz
Aug 1, 1981·Arthritis and Rheumatism·N Talal
Feb 1, 1985·Arthritis and Rheumatism·R G Lahita
Nov 30, 2000·Current Treatment Options in Neurology·A Siva, I Fresko

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