Treatment of Buruli ulcer desease by excision and skin graft

Annales de chirurgie plastique et esthétique
D OuattaraH Asse

Abstract

Buruli ulcer is the most common mycobacteria disease after leprosy and tuberculosis. The purpose of our study is to make our contribution to the surgical treatment of Buruli ulcer and to asses our results. One hundred eighteen patients presenting progressive Buruli ulcers were operated on. The surgical procedure included excisions for necrotic lesions and grafts for clean wounds. The results were estimated on the time of hospitalization and appearance of complications. Seventy-three patients (62%) were subjected to excision followed by thin skin grafts and 35 patients (30%) were subjected to grafts only. The number of excision times varies from 1 to 7 per patient and from 1 to 4 for the skin grafts. All our patients heal within a period of 120 days with extremes going from 14 to 265 days. We deplored 26 complications (22%): eight new focus, seven infectious complications, six recurrences, five stiffnesses and ankyloses. The treatment of Buruli ulcer by excision and grafts is efficient but does not prevent recurrences and new focus from happening and for their prevention, it is necessary to discover pharmaceutical molecules that are efficient on Mycobacterium ulcerans.

References

Nov 30, 2006·Advances in Skin & Wound Care·Thomas A Kwyer, Edwin Ampadu
Mar 2, 2018·Journal of the American Psychiatric Nurses Association·María José Aguilar-CorderoNorma Mur-Villar

Citations

May 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·T S van der WerfA J Knell
Jan 1, 1973·Transactions of the Royal Society of Tropical Medicine and Hygiene·D J Barker

Related Concepts

Necrosis
Tuberculosis
Avant
Equus asinus
anti-leprosy vaccine
Mycobacterium ulcerans (bacteria)
Atypical Mycobacterial Infection, Disseminated
Recurrence (Disease Attribute)
Wound Healing
Leprosy

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