PMID: 9180705Jun 1, 1997Paper

Treatment of capillary vascular malformation (port-wine stains) with photochemotherapy

Plastic and Reconstructive Surgery
X X LinT S Chang

Abstract

One-hundred and thirty patients (85 female, 45 male) with port-wine stains were treated with photodynamic therapy, also called photochemotherapy, which recently has become acknowledged as effective for a variety of malignant tumors. Probably based on the photochemical reaction with the generation of toxic species, photochemotherapy results in endothelial cell injury and death of abnormal capillaries under overlying epidermis. A retrospective review of 118 available patients with port-wine stains reveals that 98.3 percent responded to photochemotherapy with varying degrees of success after one-time treatment. Results were reported under a simple classification system ranging from ordinary to dilated to posttreatment type. In the ordinary group, the results evaluated as excellent, good, fair, and poor were 37.8, 53.7, 8.5, and 0 percent, respectively, before a second treatment; the treated area was an average of 9.8 (range 7 to 13) cm in diameter. In addition, hypertrophic scars, permanent hyperpigmentation, and hypopigmentation were not seen based on proper parameters. Photochemotherapy offers a potentially efficient and promising choice based on a completely different mechanism from that of selected photothermal therapy with th...Continue Reading

References

Mar 1, 1995·Plastic and Reconstructive Surgery·L S Bass
Jan 1, 1993·The Journal of Pediatrics·M P GoldmanJ Ruiz-Esparza

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Citations

Feb 14, 2008·Lasers in Medical Science·C Z LiY Gu
Nov 19, 2002·Clinics in Dermatology·Katrin A Salva
Nov 19, 2002·Clinics in Dermatology·Edith OrionRonni Wolf
Dec 20, 2002·Clinics in Dermatology·Alex Zvulunov, Aryeh Metzker
Aug 22, 2000·The British Journal of Dermatology·C L Currie, B E Monk
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Dec 4, 2012·Photodiagnosis and Photodynamic Therapy·Kai-Hua YuanZheng Huang
Feb 7, 2012·Journal of the American Academy of Dermatology·Jennifer K ChenMichal Heger
Sep 1, 2007·Photodiagnosis and Photodynamic Therapy·Kai-Hua Yuan, Zheng Huang
Mar 1, 2007·Photodiagnosis and Photodynamic Therapy·Zhong-Ping QinXue-Jian Liu
Nov 8, 2011·Lasers in Surgery and Medicine·Fernanda H SakamotoR Rox Anderson
Jun 5, 2012·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Shengxiu LiuXuejun Zhang
Feb 6, 2016·Archives of Plastic Surgery·Sang Min ParkIn Sook Lee
Aug 8, 2002·Journal of Clinical Laser Medicine & Surgery
Jul 28, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·T WangX Lin
Oct 19, 2005·Dermatologic Therapy·Susanne Astner, R Rox Anderson

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