Treatment of Chronic Hepatitis C in Patients Receiving Opioid Agonist Therapy: A Review of Best Practice

Infectious Disease Clinics of North America
Brianna L NortonAlain H Litwin

Abstract

Injection drug use is the most common transmission route for hepatitis C. High rates of infection are observed among individuals on opioid agonist therapy. Although people who inject drugs carry the highest burden, few have initiated treatment. We present a comprehensive review of the evidence on the efficacy of HCV medications, drug-drug interactions, and barriers to and models of care. Studies have demonstrated comparable efficacy for individuals who are on opioid agonist therapy compared with those who are not. We propose that a strategy of treatment and cure-as-prevention is imperative in this population to curb the hepatitis C epidemic.

Citations

Nov 30, 2019·The Journal of Antimicrobial Chemotherapy·Julian SureyAlistair Story
Jul 30, 2020·Seminars in Liver Disease·Jean-Michel PawlotskyJeffrey V Lazarus
Dec 15, 2020·The International Journal on Drug Policy·Vito FioreSergio Babudieri

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

The Lancet Infectious Diseases
Avina Sarna, Samiran Panda
The International Journal on Drug Policy
Jason GrebelyInternational Network for Hepatitis in Substance Users
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Jacob Meacham Smith, Josiah D Rich
The Lancet Infectious Diseases
Peter J White, Ibrahim Abubakar
© 2022 Meta ULC. All rights reserved