Treatment of depression for patients with multiple sclerosis in neurology clinics.

Multiple Sclerosis : Clinical and Laboratory Research
D C MohrE S Tasch

Abstract

The objective of this study was to examine the adequacy of antidepressant pharmacotherapy in a sample of patients with multiple sclerosis (MS) treated by neurologists. MS patients under the care of neurologists were recruited from a large health maintenance organization. Major depressive disorder (MDD) was diagnosed using a structured telephone interview. Antidepressant treatment data were obtained from the HMO pharmacy database. Study participants included 260 patients with MS treated by 35 neurologists. A total of 67 (25.8%) patients met the criteria for MDD. Among the patients with MDD, 65.6% received no antidepressant medication, 4.7% received subthreshold doses from their neurologists, 26.6% received doses at threshold, and 3.1% received doses exceeding threshold. Depression was undertreated by the neurologists treating this sample of patients with comorbid MS and MDD. Potential solutions are discussed.

References

Nov 1, 1990·The American Journal of Psychiatry·R B Schiffer, N M Wineman
Jul 1, 1993·Journal of Psychiatric Research·G E SimonM VonKorff
Mar 1, 1996·Neurology·A D SadovnickD W Paty
Dec 1, 1995·Journal of General Internal Medicine·G E SimonP Robinson
Oct 1, 1996·Archives of General Psychiatry·H C SchulbergJ L Coulehan
Jul 1, 1997·Archives of Family Medicine·H C SchulbergJ L Coulehan
Jul 1, 1997·Journal of General Internal Medicine·D S BrodyT L Thompson
Nov 14, 1997·The American Journal of Psychiatry·P RohdeJ R Seeley
Feb 7, 2001·Archives of General Psychiatry·A S YoungK B Wells
Nov 29, 2001·Multiple Sclerosis : Clinical and Laboratory Research·M P AmatoL Rossi
Nov 1, 2002·Journal of the Neurological Sciences·Vallabh Janardhan, Rohit Bakshi
Nov 2, 2002·The American Journal of Psychiatry·Lydia ChwastiakGeorge H Kraft
Jul 29, 2003·Psychosomatic Medicine·David C MohrAlison Goldberg
Aug 26, 2004·JAMA : the Journal of the American Medical Association·Gregory E SimonMichael Von Korff

❮ Previous
Next ❯

Citations

Sep 11, 2010·The Clinical Neuropsychologist·L B Strober, P A Arnett
Oct 25, 2013·International Review of Psychiatry·Nicole LichtblauHubertus Himmerich
Sep 25, 2015·Annals of General Psychiatry·Khadijeh MohammadiAli Montazeri
Dec 15, 2015·International Journal of MS Care·Aida RaissiScott B Patten
Jan 10, 2016·Multiple Sclerosis : Clinical and Laboratory Research·Helge HasselmannStefan M Gold
Mar 10, 2017·Multiple Sclerosis : Clinical and Laboratory Research·Viral P PatelAnthony Feinstein
Dec 22, 2017·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Kiira TietjenJeremy Dietz
May 5, 2018·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Kimberly R ChapmanMary Beth Spitznagel
Jan 21, 2009·Multiple Sclerosis : Clinical and Laboratory Research·R A MarrieT Vollmer
Sep 21, 2007·Multiple Sclerosis : Clinical and Laboratory Research·S Kern, T Ziemssen
Dec 17, 2009·Multiple Sclerosis : Clinical and Laboratory Research·A FeinsteinN J Lobaugh
Jan 8, 2013·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Mathias SundgrenTom Brismar
Mar 22, 2013·Psychology, Health & Medicine·Lara M SteplemanTricia Brands
Aug 1, 2015·Journal of Clinical and Experimental Neuropsychology·Lauren B Strober, Peter A Arnett
Apr 19, 2007·Multiple Sclerosis : Clinical and Laboratory Research·D C MohrE S Tasch
Mar 13, 2008·Der Nervenarzt·S KernT Ziemssen
Sep 23, 2009·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Lorraine J Phillips, Alexa K Stuifbergen
Aug 13, 2014·Nature Reviews. Neurology·Anthony FeinsteinCraig Moore
May 27, 2015·The Journal of Comparative Neurology·Leonie A K LöfflerBirgit Derntl
Nov 5, 2014·Applied Psychophysiology and Biofeedback·Azadeh ChoobforoushzadehMohammad Reza Abedi
Jan 24, 2014·International Journal of MS Care·Stephen S KirzingerAndrew Bryce Crush
Jan 19, 2018·JMIR Research Protocols·Ruth Ann MarrieCharles N Bernstein
Feb 9, 2018·CNS Drugs·Claudio SolaroFabio Giuseppe Masuccio
Jun 4, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·V L MalyginYa V Malygin
Jul 18, 2008·Multiple Sclerosis : Clinical and Laboratory Research·G H KraftH Starks
Oct 16, 2013·Multiple Sclerosis : Clinical and Laboratory Research·Anthony FeinsteinRobert Motl
Dec 20, 2007·International Clinical Psychopharmacology·Lars Vedel KessingPer Kragh Andersen
Nov 8, 2011·Multiple Sclerosis : Clinical and Laboratory Research·Anthony Feinstein
Jan 24, 2014·International Journal of MS Care·Judy Ann WollinRex D Simmons
May 15, 2016·Journal of Neurology·Sven SchipplingBarry Arnason
May 26, 2017·Multiple Sclerosis International·Sandipan BhattacharjeeTerri Warholak
Mar 30, 2021·Multiple Sclerosis and Related Disorders·C Danielle JonesBrian M Sandroff

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
P O'Connor, L Lee
The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
James J MarriottPaul W O'Connor
© 2022 Meta ULC. All rights reserved