Treatment of depression in cancer and non-cancer patients in German neuropsychiatric practices

Psycho-oncology
Louis JacobMatthias Kalder

Abstract

The aim of this study is to analyze the use of antidepressants in German patients with and without cancer. This study included patients with cancer diagnosed with depression in German neuropsychiatric practices between 2004 and 2013. Each patient was matched for age, gender, health insurance, physician, and index year with a depressed, cancer-free control. The share of patients and controls receiving medical therapy within 1 year after depression diagnosis and the proportion of subjects treated with tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, or benzodiazepines were analyzed. A total of 604 depressed cancer patients and 604 depressed controls were included. There are 27.6% of patients that had breast cancer, 13.3% malignant neoplasms of the lymphoid or hematopoietic tissue, 12.5% brain tumors, 8.3% prostate cancer, and 10.0% cancer of the digestive organs. After 1 year of follow up, 66.5% of patients and 72.8% of controls had received antidepressant drugs (p = 0.017). Tricyclic antidepressants was given less frequently to patients than to controls (31.2% vs 38.2%, p-value = 0.011). By contrast, 7.0% of patients with cancer and 4.2% of controls received be...Continue Reading

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Citations

Aug 10, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Julia DrosselmeyerKarel Kostev
Sep 7, 2016·Journal of Psychiatric Research·Louis Jacob, Karel Kostev
Sep 14, 2016·Pain Practice : the Official Journal of World Institute of Pain·Louis Jacob, Karel Kostev
May 11, 2017·Current Psychiatry Reports·Rosangela CarusoLuigi Grassi
Jul 26, 2017·Therapeutic Advances in Psychopharmacology·Louis JacobKarel Kostev
Nov 26, 2021·Cancer Medicine·Alexander S QianJames D Murphy

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