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Treatment of exocrine pancreatic insufficiency with fungal lipase (author's transl)

Arzneimittel-Forschung

Nov 1, 1975

H Pointner, U Flegel

PMID: 1053

Abstract

7 patients suffering from severe exocrine pancreatic insufficiency have been treated with a lipolytic enzyme extracted from Rhizopus arrhizus. Comparing the fungal lipase with a placebo the drug lowered the daily stool weight from 809 g to 443 g on an average, i.e. by 45.2%. The steator...read more

Mentioned in this Paper

Exocrine Pancreatic Insufficiency
Rhizopus arrhizus antigen
Pancreatitis
Peptide Hydrolases
Chronic Disease
Endopeptidases
Proteolytic Enzyme
Celiac Disease
Triacylglycerol Lipase Measurement
Rhizopus
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Treatment of exocrine pancreatic insufficiency with fungal lipase (author's transl)

Arzneimittel-Forschung

Nov 1, 1975

H Pointner, U Flegel

PMID: 1053

DOI:

Abstract

7 patients suffering from severe exocrine pancreatic insufficiency have been treated with a lipolytic enzyme extracted from Rhizopus arrhizus. Comparing the fungal lipase with a placebo the drug lowered the daily stool weight from 809 g to 443 g on an average, i.e. by 45.2%. The steator...read more

Mentioned in this Paper

Exocrine Pancreatic Insufficiency
Rhizopus arrhizus antigen
Pancreatitis
Peptide Hydrolases
Chronic Disease
Endopeptidases
Proteolytic Enzyme
Celiac Disease
Triacylglycerol Lipase Measurement
Rhizopus

Similar Papers Found In These Feeds

Exocrine Glands

Exocrine glands are a specific type of gland which contains ducts that secrete a specialized substance to a surface, such as the salivary glands, respiratory and gastrointestinal glands. Diseases can affect the exocrine glands and impair their normal functioning. Discover the latest research on exocrine glands here.

Oxygenation & Hydroxylation

Oxygenation is a chemical production that introduces oxygen atom into an organic compound. Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound. In biochemistry, hydroxylation reactions are often facilitated by enzymes called hydroxylases. Cytochrome P450 (CYP) enzymes are expressed mainly in the liver and are active in mono-oxygenation and hydroxylation of various xenobiotics, including drugs and alcohols, as well as that of endogenous compounds such as steroids, bile acids, prostaglandins, leukotrienes and biogenic amines. Here is the latest research.

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