PMID: 3214091Jan 1, 1988Paper

Treatment of fungal infections with semisynthetic derivatives of amphotericin B alpha

Annals of the New York Academy of Sciences
P D HoeprichC P Schaffner

Abstract

AME appeared to be as effective as AmB in the treatment of mycoses in humans. AME was much less nephrotoxic than AmB, and was better tolerated in terms of rapid onset and reversible adverse reactions. AME may be more ototoxic than AmB. AME, even as AmB and OAME, may cause neurotoxicity and leukoencephalopathy, particularly when high doses are given for long periods.

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Citations

Jan 1, 1989·Diagnostic Microbiology and Infectious Disease·R E NeihartC Liu
Nov 5, 1998·Journal of Controlled Release : Official Journal of the Controlled Release Society·B G YuG S Kwon
Feb 1, 1990·Antimicrobial Agents and Chemotherapy·J BrajtburgG Medoff
Mar 1, 1993·Antimicrobial Agents and Chemotherapy·K R ReuhlC P Schaffner
Jan 1, 1992·Scandinavian Journal of Infectious Diseases·J E HansenL R Mathiesen

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