Treatment of gastrointestinal bleeding with hemostatic powder (TC-325): a multicenter study

Surgical Endoscopy
Ariadna Iraís Ramírez-PoloFélix I Téllez-Ávila

Abstract

Hemostatic powder (TC-325) is a new tool for treatment of gastrointestinal bleeding that allows the treatment of large surfaces with active bleeding. The aim was to describe the initial success of TC-325 for the control of GI bleeding. We did a multicenter cohort study with patients admitted to the endoscopy service for GI bleeding. A format was generated to standardize the information obtained in each center. It was determined whether this treatment had been used as a single therapy or as a combination therapy. Descriptive statistics with medians and ranges, or averages with SD according to distribution. Eighty-one patients with 104 endoscopic procedures were included. The median number of endoscopic procedures was 1 (1-3). In the first procedure, the initial success rate was 98.8% (n = 80), failure rate was 1.2% (n = 1), and rebleeding rate was 20% (n = 16). The majority of rebleeding cases occurred within the first 3 days (12/16, 75%). There was no association between rebleeding and etiology (malignant or benign; P = 0.6). In first procedure, 44 (54%) cases had monotherapy with TC-325 and 37 (46%) cases had a combined endoscopic therapy. There were no differences in initial success or rebleeding rates when TC-325 was used as...Continue Reading

References

Mar 27, 2012·Gastrointestinal Endoscopy·Louis-Michel Wong Kee SongSarah A Rodriguez
Feb 16, 2013·Gastrointestinal Endoscopy·Harry R Aslanian, Loren Laine
Sep 22, 2016·Endoscopy International Open·Rapat PittayanonRungsun Rerknimitr
Sep 23, 2016·The New England Journal of Medicine·Alfred I Lee, Christopher A Tormey
Sep 23, 2016·The New England Journal of Medicine·Geoffrey Wool

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