Treatment of glomus jugulare tumors with gamma knife radiosurgery

The Laryngoscope
Philip G ChenGeorge T Hashisaki

Abstract

Surgical resection, preoperative embolization, radiation therapy, and stereotactic radiosurgery have been used to treat glomus jugulare tumors (GJT). However, the optimal treatment of these tumors remains unclear. The authors report their data on treatment of GJTs with gamma knife radiosurgery (GKS). Retrospective review and pooled analysis. Fifteen patients (nine female, six male) were treated with GKS at a single tertiary care institution for GJTs over a 14-year period. Criteria for selection included GKS followed by at least one posttreatment radiographic image, and volumetric analysis was performed. A required 15% change in tumor volume was considered real. Pooled analysis was performed to compare outcomes with other series. The mean total radiologic follow-up was 43.2 months. The mean dose-to-the tumor margin was 14.6 Gy. The mean tumor size at treatment was 7.3 cc and 6.3 cc at last follow-up. After treatment, seven tumors decreased (46.7%), five remained unchanged (33.3%), and three (20%) grew on imaging. Treatment failures received a mean marginal dose of 13.2 Gy compared with 15.1 Gy for treatment successes (P =.08). Overall tumor control rate after GKS in the existing literature with inclusion of the present study is ...Continue Reading

References

Nov 1, 1978·The Journal of Laryngology and Otology·U Fisch
Apr 1, 1992·Cancer·J M LarnerW C Constable
Jan 1, 1991·Acta Oncologica·J SkołyszewskiJ Pszon
Aug 1, 1991·International Journal of Radiation Oncology, Biology, Physics·L A NedziJ S Loeffler
Apr 1, 1991·Journal of Neurosurgery·D KondziolkaJ C Flickinger
Aug 1, 1990·The Laryngoscope·J O BoyleS W Coulthard
Jul 1, 1982·Archives of Otolaryngology·C G JacksonP F Harris
Jul 15, 1983·Cancer·E K ReddyG V Hartman
Jan 1, 1994·Acta neurochirurgica·L D WatkinsL Symon
Nov 1, 1993·The Laryngoscope·V Carrasco, J Rosenman
Jun 1, 1997·International Journal of Radiation Oncology, Biology, Physics·R L FooteS E Schild
Jan 23, 1999·The Laryngoscope·S ManolidisM E Glasscock
Apr 14, 1999·The Laryngoscope·H R BrinerU Fisch
Oct 28, 1999·Acta neurochirurgica·S EustacchioG Pendl
Jan 26, 2000·The Laryngoscope·J A JordanC A Giller
May 12, 2001·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·C G JacksonM E Glasscock
Nov 7, 2001·Minimally Invasive Neurosurgery : MIN·W SaringerK Kitz
Jan 1, 2003·Journal of Neurosurgery·Ossama Al-Mefty, Aramis Teixeira
Aug 12, 2003·International Journal of Radiation Oncology, Biology, Physics·Mark E Linskey, Peter A S Johnstone
Aug 27, 2004·Neurosurgical Focus·Oren N GottfriedWilliam T Couldwell
Aug 27, 2004·Neurosurgical Focus·Bruce E Pollock
Aug 27, 2004·Neurosurgical Focus·Michael LimSteven D Chang
Nov 6, 2004·Journal of Neuro-oncology·Ketan R Bulsara, Ossama Al-Mefty
Nov 8, 2005·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Seth N WillenCliff A Megerian
May 10, 2006·International Journal of Radiation Oncology, Biology, Physics·Aaron J KrychMichael J Link
Sep 7, 2006·Neurosurgery·Massimo GerosaAlbino Bricolo
Jan 1, 1996·Skull Base Surgery·R KuhweideU Fisch
Sep 27, 2007·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Martin HenzelRita Engenhart-Cabillic
Nov 22, 2007·The Laryngoscope·Maura CosettiSimon Parisier
Apr 2, 2008·Current Oncology Reports·Michael E Kupferman, Ehab Y Hanna
Dec 1, 2006·Journal of Neurosurgery·Mohammad Ali BitarafSoraya Salmanian
Sep 18, 2008·Current Opinion in Otolaryngology & Head and Neck Surgery·Maroun T Semaan, Cliff A Megerian
Jan 29, 2009·Stereotactic and Functional Neurosurgery·Jonathan P MillerRobert J Maciunas

❮ Previous
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Citations

May 4, 2012·Current Opinion in Otolaryngology & Head and Neck Surgery·Aristides Sismanis
Jun 12, 2012·Journal of Neurosurgery·Jason P SheehanL Dade Lunsford
Mar 19, 2014·American Journal of Otolaryngology·Julian KünzelHeinrich Iro
Apr 23, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Sampath Chandra PrasadMario Sanna
Jan 17, 2015·Surgical Neurology International·Ali HaratiRolf Schultheiß
Dec 12, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Andrea BacciuMario Sanna
Apr 20, 2013·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Jeffrey T Vrabec
Jun 6, 2013·The Laryngoscope·Jason Y K ChanChristine G Gourin
Jun 9, 2014·European Annals of Otorhinolaryngology, Head and Neck Diseases·P Tran Ba Huy
Jan 22, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Leonie T van HulsteijnOlaf M Dekkers
Jul 6, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Sigolène Galland-GirodetAymeri Huchet
Oct 2, 2012·European Annals of Otorhinolaryngology, Head and Neck Diseases·M MakeieffC-A Righini
Mar 15, 2015·Otolaryngologic Clinics of North America·George B WannaMatthew L Carlson
May 4, 2015·Journal of Neurointerventional Surgery·Caterina MichelozziChristophe Cognard
Jul 9, 2016·Journal of Neurosurgery·Ramez IbrahimMatthias Radatz
Oct 8, 2013·Seminars in Nuclear Medicine·David TaïebKarel Pacak
Jul 29, 2016·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Mitchell R DobberpuhlMatthew L Bush
Jan 26, 2017·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Tyler W WinfordEric R Oliver
Dec 10, 2017·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·T T G JansenH P M Kunst
Dec 2, 2017·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Neil S PatelMatthew L Carlson
Aug 21, 2018·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Scott ShapiroAdam Cassis
May 28, 2019·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·E ZanolettiD Zanetti
Aug 25, 2016·Cancer Control : Journal of the Moffitt Cancer Center·Kenneth Hu, Mark S Persky
Dec 19, 2020·Journal of Cerebrovascular and Endovascular Neurosurgery·Charbel Ishak, Varun Danda

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