Treatment of hepatitis C-virus-related glomerulonephritis

Kidney International
Nassim KamarL Alric

Abstract

Membranoproliferative glomerulonephritis (MPGN) associated with type II cryoglobulinemia is the predominant type of hepatitis C virus (HCV)-related glomerulonephritis. The blockade of the renin-angiotensin system, as well as a combined anti-HCV therapy that associates standard or pegylated alpha-interferon with ribavirin, are mandatory in all patients experiencing an HCV-related glomerulonephritis. In patients with nephrotic-range proteinuria and/or progressive renal failure, immunosuppressive therapy is necessary. Rituximab, the monoclonal anti-CD20 antibody that selectively targets the B cells, seems to be as least as efficient as cyclophosphamide. Because it is also better tolerated, it should be preferred to cyclophosphamide. During the acute phase, plasmapheresis and steroid pulses can be used. However, future prospective, controlled, and randomized studies are still required to establish evidence-based guidelines to treat HCV-related glomerulopathies.

References

Mar 17, 1994·The New England Journal of Medicine·R MisianiG Vendramin
Dec 16, 1998·Journal of the American Society of Nephrology : JASN·G S MarkowitzV D D'Agati
Jan 16, 2002·Current Opinion in Rheumatology·Patrice CacoubLaurent Alric
Oct 29, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Alaa A SabryAbdel Meguid El-Nahas
Feb 1, 2003·Blood·Francesco ZajaGianfranco Ferraccioli
Jun 28, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Nassim KamarLionel Rostaing
Aug 5, 2003·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Annette BruchfeldRobert Schvarcz
Jan 9, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Nassim KamarLionel Rostaing
Mar 26, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Laurent AlricPatrice Cacoub
Oct 21, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Dario RoccatelloLuigi Massimino Sena
May 25, 2005·Lancet·S J Chadban, R C Atkins
Dec 24, 2005·Transplantation·Grégoire BasseLionel Rostaing
Sep 19, 2006·Transplantation Proceedings·G BasseL Rostaing

❮ Previous
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Citations

Mar 24, 2007·Digestive Diseases and Sciences·Maria Pina DoreGiuseppe Realdi
Apr 15, 2008·Current Opinion in Nephrology and Hypertension·Charles E Alpers, Kelly D Smith
Feb 3, 2012·Transplantation·Nassim KamarLionel Rostaing
Mar 14, 2008·Journal of the American Society of Nephrology : JASN·Shunhua GuoCharles E Alpers
Jun 26, 2009·World Journal of Gastroenterology : WJG·Masami MinemuraYukihiro Shimizu
Jan 19, 2012·World Journal of Gastroenterology : WJG·Roberto J Carvalho-FilhoAntonio Eduardo B Silva
Oct 4, 2012·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Abdullah S AlghamdiUNKNOWN Saudi Association for the Study of Liver Diseases and Transplantation
Sep 12, 2007·Seminars in Immunopathology·Saraladevi NaickerStewart Goetsch
Feb 20, 2007·Postgraduate Medical Journal·Gerald S BraunHolger Schmid
Nov 26, 2009·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Ingrid Lyngved ØdegårdHelge Scott
Sep 4, 2015·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Tomoyuki OtsukaShuichi Tsuruoka
Mar 26, 2013·Clinics and Research in Hepatology and Gastroenterology·Nassim KamarLionel Rostaing
Apr 20, 2010·Enfermedades infecciosas y microbiología clínica·UNKNOWN Panel de expertos del Grupo de Estudio de Sida (GESIDA) y del Plan Nacional sobre el Sida (PNS)
Oct 20, 2009·Enfermedades infecciosas y microbiología clínica·Pere DomingoXavier Fulladosa
May 12, 2007·Mayo Clinic Proceedings·Travis L Figanbaum, Suzanne M Norby
Aug 23, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·N KamarL Rostaing
Mar 31, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Marc G GhanyUNKNOWN American Association for the Study of Liver Diseases
Oct 1, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Sabina SabharwalRaymond T Chung
Jul 13, 2011·Liver International : Official Journal of the International Association for the Study of the Liver·Chrisoula PipiliEvangelos Cholongitas
Jan 27, 2018·BMC Gastroenterology·Rita MorettiClaudio Tiribelli
Jan 9, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Norberto PericoGiuseppe Remuzzi
Aug 19, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Norah A Terrault, Deborah B Adey
Dec 17, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Flavio VincentiGerald Appel
Jun 30, 2009·Clinical Chemistry·Kareena L SchnablKhosrow Adeli
Jan 3, 2013·The International Journal of Artificial Organs·Maria Francesca DonatoPiergiorgio Messa
Oct 1, 2013·Frontline Gastroenterology·David G Samuel, Ian W Rees
Apr 10, 2007·The International Journal of Artificial Organs·F FabriziP Martin
Dec 18, 2018·Frontiers in Medicine·Narayan Prasad, Manas Ranjan Patel
Mar 1, 2013·Hepatology International·Aline Gonzalez Vigani

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