Treatment of inappropriate sinus tachycardia with ivabradine in a patient with postural orthostatic tachycardia syndrome and a dual chamber pacemaker

Pacing and Clinical Electrophysiology : PACE
Sitara KhanChristopher Rinaldi

Abstract

We present the case of a 44-year-old woman with postural orthostatic tachycardia syndrome (POTS) and a dual chamber pacemaker. The patient suffered from inappropriate sinus tachycardia that had been resistant to treatment with traditional rate-slowing medications. Ivabradine--the specific sinus node I(f) current inhibitor--was used to successfully lower the heart rate. The patient had no evidence of POTS on repeat autonomic function testing, and there was a corresponding symptomatic benefit. We propose that this class of drugs, the use of which is established as antianginals, should be considered in patients with resistant inappropriate sinus tachycardia.

References

Oct 28, 2005·Clinical Cardiology·David Spodick
Nov 3, 2005·Nature Clinical Practice. Cardiovascular Medicine·Shamil Yusuf, A John Camm
Oct 24, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Victoria EwanJulia L Newton

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Citations

Sep 23, 2010·Naunyn-Schmiedeberg's Archives of Pharmacology·Stephan ZellerhoffStefan Kääb
Jun 28, 2011·European Journal of Clinical Pharmacology·Knut Tore Lappegård, Elisabet Nordmo
Nov 11, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Claire McDonaldJulia L Newton
Jul 10, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Pawel PtaszynskiJerzy K Wranicz
Jul 12, 2012·Journal of Geriatric Cardiology : JGC·Howraa AbedLe-Xin Wang
Oct 4, 2014·Autonomic Neuroscience : Basic & Clinical·James C CorkalKurt Kimpinski
Dec 10, 2009·Wiener klinische Wochenschrift·Peter Rakovec
Jun 15, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Saurabh Kumar, Jitendra Vohra
Oct 13, 2009·Medicina clínica·Nieves Romero-RodríguezAngel Martínez Martínez
Jul 4, 2009·Pacing and Clinical Electrophysiology : PACE·Pierre-Francois WinumPatrick Messner-Pellenc
Mar 21, 2013·Pacing and Clinical Electrophysiology : PACE·Juan Benezet-MazuecosEster Macía
May 16, 2014·Cardiovascular Therapeutics·Ivano BonadeiMarco Metra
Mar 18, 2010·Journal of Cardiovascular Electrophysiology·Antonella SetteLeonardo Calò
Oct 14, 2009·Pacing and Clinical Electrophysiology : PACE·Lucio CapulziniPedro Brugada
Feb 25, 2015·Journal of Diabetes and Its Complications·Christian MeyerDan Ziegler
Mar 17, 2012·Heart & Lung : the Journal of Critical Care·Sameer ChadhaJacob Shani
Jan 14, 2018·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Megan E GeeEmily J A Young
Feb 20, 2010·Circulation Research·Dario DiFrancesco
Mar 4, 2018·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Jangsup MoonKon Chu
Oct 14, 2017·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Grazia Delle DonnePiers E F Daubeney
Apr 22, 2019·BMJ Case Reports·Muhammad Arslan CheemaKhadija Cheema
Feb 20, 2021·Journal of the American College of Cardiology·Pam R TaubJonathan C Hsu

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