Treatment of leishmaniasis with miltefosine: 2008 status

Expert Opinion on Drug Metabolism & Toxicology
Jonathan Josh Berman

Abstract

Miltefosine is the first recognized oral treatment for leishmaniasis. It was first registered, in 2002, for Indian visceral leishmaniasis, and was reviewed by the present author in 2005. Miltefosine is now being used for the full range of clinical leishmaniasis. The present review addresses non-clinical and clinical advances since 2005. PubMed was accessed for all articles on miltefosine from 2005 to 2008. Miltefosine is effective and can be recommended for visceral disease in India and in Ethiopia, and for cutaneous disease in Colombia and Bolivia. For unusual forms of disease that require long periods of treatment such as diffuse cutaneous leishmaniasis and post-kala-azar dermal leishmaniasis, oral miltefosine is probably the treatment of choice.

Associated Clinical Trials

References

Dec 15, 1990·Annals of Internal Medicine·E D FrankeJ D Berman
Nov 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·J SotoP Olliaro
Nov 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·N C HepburnJ A Hunter
Oct 6, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A Llanos-CuentasJ Marr
Nov 29, 2002·The New England Journal of Medicine·Shyam SundarJonathan Berman
Jul 25, 2003·Antimicrobial Agents and Chemotherapy·F Javier Pérez-VictoriaFrancisco Gamarro
Sep 30, 2003·The Journal of Biological Chemistry·F Javier Pérez-VictoriaSantiago Castanys
Oct 3, 2003·International Journal of Antimicrobial Agents·Karin SeifertSimon L Croft
Dec 31, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sujit K BhattacharyaJonathan D Berman
Jul 27, 2004·Antimicrobial Agents and Chemotherapy·Navin K Verma, Chinmoy S Dey
May 24, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christine SchranerHuldrych F Günthard
Jul 15, 2005·Expert Opinion on Pharmacotherapy·Jonathan Berman
Dec 6, 2005·Transactions of the Royal Society of Tropical Medicine and Hygiene·Shyam SundarVikram Singh
Apr 25, 2006·Annals of Tropical Medicine and Parasitology·A Dejenie BelayR N Davidson
Jun 27, 2006·International Journal of Dermatology·Olga ZerpaJacinto Convit
Jun 29, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Koert RitmeijerRobert N Davidson
Aug 31, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Caryn BernJorge Alvar
Jan 5, 2007·Indian Journal of Pediatrics·Utpal Kant SinghB P Jayswal
Jan 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J SotoJ Berman
Jan 24, 2007·Antimicrobial Agents and Chemotherapy·M RakotomangaP M Loiseau
Jan 26, 2007·Pharmaceutical Research·Cécile MénezGillian Barratt
Feb 7, 2007·Antimicrobial Agents and Chemotherapy·Juan Román Luque-Ortega, Luis Rivas
Mar 10, 2007·Apoptosis : an International Journal on Programmed Cell Death·Caroline ParisJacqueline Bréard
Mar 21, 2007·Antimicrobial Agents and Chemotherapy·Zhongsheng TongSharon C A Chen
Apr 20, 2007·The British Journal of Dermatology·O ZerpaJ Convit
Apr 20, 2007·International Journal of Dermatology·Marija StojkovicRobert N Davidson
Jun 22, 2007·The New England Journal of Medicine·Shyam SundarSujit K Bhattacharya
Jul 13, 2007·The Journal of Infectious Diseases·Sujit Kumar BhattacharyaNirmal Kumar Ganguly
Sep 14, 2007·Scandinavian Journal of Infectious Diseases·Jesús TroyaMiguel Górgolas
May 24, 2008·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Angela NeubUlrich Amon
Jun 4, 2008·Antimicrobial Agents and Chemotherapy·Thomas P C DorloPeter J de Vries

❮ Previous
Next ❯

Citations

Oct 2, 2012·Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents·Jiangtao GaoStephen J Cutler
Jul 12, 2012·The Journal of Antimicrobial Chemotherapy·Anny FortinLouis Maes
Oct 5, 2010·Current Opinion in Infectious Diseases·Frederick S Buckner, Nazlee Navabi
Jan 13, 2010·The American Journal of Tropical Medicine and Hygiene·Dennis TappeAugust Stich
Mar 10, 2012·The American Journal of Tropical Medicine and Hygiene·Henry W Murray
Jul 15, 2016·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·Eglal I AmerShereen F Mossallam
Dec 18, 2014·International Journal for Parasitology. Drugs and Drug Resistance·Rafael Balaña-FouceRosa M Reguera
Jun 16, 2010·Drug Development and Industrial Pharmacy·Sheila J ThorntonEllen K Wasan
Jun 26, 2012·Expert Opinion on Drug Delivery·Guilherme CarneiroLucas Antônio Miranda Ferreira
May 13, 2011·The British Journal of Dermatology·V RameshP Salotra
Jun 11, 2010·International Journal of Dermatology·Sujay KhandpurVinod K Sharma
Apr 8, 2015·Chemical Biology & Drug Design·Edson R da SilvaTalita H da Costa
Jun 20, 2015·BioMed Research International·Carlos Gustavo Vieira de MoraisPatrícia Maria Lourenço Dutra
Jul 25, 2014·International Journal for Parasitology. Drugs and Drug Resistance·Katherine T AndrewsTina S Skinner-Adams
Jul 3, 2013·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Carlos MunozFlorian Lang
Jan 10, 2012·International Journal of Antimicrobial Agents·Joseane Lima Prado GodinhoJuliany Cola Fernandes Rodrigues
Jan 9, 2010·Trends in Parasitology·Alexis NzilaTim Niehues
Oct 23, 2009·FEMS Immunology and Medical Microbiology·Andrea CavalliMaria Laura Bolognesi
Feb 17, 2015·International Journal of Medicinal Chemistry·Melanie Loedige
Jun 12, 2016·Pharmacology & Therapeutics·Paul-Alain JaffrèsChristophe Vandier
Oct 22, 2015·Chemical Society Reviews·Víctor GutiérrezMarcelo Calderón
May 3, 2018·Expert Opinion on Therapeutic Targets·Shyam Sundar, Bhawana Singh
Sep 1, 2011·Drug Development Research·Kathryn M DupnikSelma M B Jeronimo
Dec 3, 2013·MMW Fortschritte der Medizin·Peter Stingl
Aug 14, 2020·Microorganisms·Nnamdi M IkeoguJude E Uzonna
Jun 26, 2021·European Journal of Medicinal Chemistry·Ojasvi GuptaVikramdeep Monga
Aug 13, 2021·Zeitschrift für Rheumatologie·Tomas Jelinek

❮ Previous
Next ❯

Related Concepts

Related Papers

The American Journal of Tropical Medicine and Hygiene
Iván VélezErwin Rodríguez
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
J SotoJ D Berman
© 2022 Meta ULC. All rights reserved