PMID: 7543209Mar 1, 1995Paper

Treatment of local recurrences of rectal carcinoma

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
G J FrykholmB Glimelius

Abstract

From 1978-1992, 159 patients were treated for local recurrences of rectal carcinoma. They could be subdivided into three groups according to the type of primary treatment given; 82 patients underwent primary surgery without irradiation, 37 patients had preoperative and 40 patients postoperative radiotherapy. The localizations of the recurrences and the curative and palliative potentials of surgery and radiotherapy in the treatment of local recurrences were studied. There was no difference in the localisation of the recurrences in the three groups. Median time between initial surgery and recurrence was also almost the same in the three groups and 75% of the recurrences appeared within 2 years. Twenty percent of the patients in the primary surgery alone group, compared with 49% and 38% in the preoperative and postoperative irradiation groups, respectively, had distant metastases at the time of the diagnosis of local recurrence. The predominant symptom from the local recurrence was pain and, after treatment of the recurrence, pain relief was registered in 63%. In 66%, 16% and 22%, respectively, of the patients in the three groups, the intention of the treatment was curative, with either radiotherapy alone, radiotherapy combined wi...Continue Reading

References

Jun 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·B D MinskyL Harrison
Oct 1, 1991·International Journal of Radiation Oncology, Biology, Physics·C S WongC N Catton
Mar 14, 1991·The New England Journal of Medicine·J E KrookJ A Mailliard
Apr 1, 1989·International Journal of Radiation Oncology, Biology, Physics·F BailletG Boisserie
Jun 6, 1985·The New England Journal of Medicine·UNKNOWN Gastrointestinal Tumor Study Group
May 1, 1986·The British Journal of Surgery·R SchiesselF Herbst
Dec 1, 1985·Diseases of the Colon and Rectum·W Dobrowsky, A P Schmid
Apr 1, 1971·Clinical Radiology·J KirkE R Watson
Jan 1, 1982·Acta Radiologica. Oncology·S Ciatto, P Pacini
Jan 1, 1984·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M OvergaardA Sell
Jan 1, 1984·The British Journal of Surgery·R K PhillipsL P Fielding
May 15, 1993·Lancet·W Silen
Jul 6, 1963·British Medical Journal·B C MorsonH J Bussey

❮ Previous
Next ❯

Citations

Mar 24, 2005·Diseases of the Colon and Rectum·Maarten VermaasJohannes H W de Wilt
Aug 17, 2006·Diseases of the Colon and Rectum·Floris T J FerenschildJohannes H W de Wilt
Sep 5, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Richard D PeznerJoshua D I Ellenhorn
Apr 5, 2001·International Journal of Radiation Oncology, Biology, Physics·M G HaddockB G Wolff
Feb 11, 1998·International Journal of Radiation Oncology, Biology, Physics·C S WongY Hao
Dec 29, 1999·International Journal of Radiation Oncology, Biology, Physics·J SeongC O Suh
Aug 20, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Bengt Glimelius
Aug 1, 2007·Clinics in Colon and Rectal Surgery·Johannes H W de WiltCornelis Verhoef
Apr 25, 2006·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R BakxJ J B van Lanschot
Nov 24, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·K KodedaS Nordgren
Mar 23, 2013·Canadian Journal of Surgery. Journal Canadien De Chirurgie·Pieter J TanisJ Jan B van Lanschot
Oct 22, 2008·World Journal of Gastroenterology : WJG·Roel BakxJ-Jan-B van Lanschot
Apr 17, 2010·International Journal of Radiation Oncology, Biology, Physics·Michael G HaddockLeonard L Gunderson
Mar 23, 2011·ANZ Journal of Surgery·Gurpreet Singh-Ranger
Oct 23, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·O ReerinkG A P Hospers
Apr 16, 1998·Seminars in Radiation Oncology·C S Wong, J D Brierley
Aug 26, 2014·Journal of the Egyptian National Cancer Institute·Wael GawadOsman Mansour
Aug 2, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Morten BraendengenBengt Glimelius
Oct 2, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mandy van den BrinkCornelis J H van de Velde
Jan 1, 2003·The Surgical Clinics of North America·Wayne S KendalHartley Stern
Feb 25, 2000·The Journal of Urology·M S GazzanigaA M Shanberg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.