PMID: 3756767Nov 15, 1986Paper

Treatment of metastatic adrenal cortical carcinoma with cisplatin and etoposide (VP-16)

Cancer
D H Johnson, F A Greco

Abstract

Two patients with metastatic adrenal cortical carcinoma were treated with cisplatin and etoposide. Both achieved a partial remission after only one cycle. One patient had a "nonfunctioning" tumor that had previously regressed on mitotane whereas the second patient presented with classical Cushing's syndrome. Although the latter patient's urinary 17-ketosteroids normalized while receiving mitotane, the tumor itself failed to regress objectively. Cisplatin plus etoposide appears to be an active combination for the treatment of metastatic adrenal cortical carcinoma.

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Citations

Sep 27, 2001·World Journal of Surgery·A P DackiwD B Evans
Sep 27, 2001·World Journal of Surgery·H AhlmanS Lindstedt
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Jul 1, 1992·World Journal of Surgery·P IcardY Chapuis

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