Treatment of metastatic sialoblastoma with chemotherapy and surgery

Pediatric Blood & Cancer
Julius X ScottTamas Revesz

Abstract

Tumors of the salivary gland are very uncommon in children. Sialoblastoma is a rare, aggressive, blastomatous, and potentially malignant congenital tumor. Distant metastases are rare. We present a case of sialoblastoma with lung metastases that developed in a 4-year-old girl adjacent to a congenital nevus in the left cheek. The tumor was inoperable at diagnosis but the largest of the pulmonary metastases was removed surgically. The patient responded well to chemotherapy and underwent surgical excision of the primary tumor, followed by three more courses of chemotherapy.

References

Oct 1, 1976·Archives of Dermatology·R L Dimond, R B Amon
Jan 1, 1988·Pediatric Pathology·G P Taylor
Feb 1, 1972·Cancer·E B CastroF W Foote
Aug 1, 1972·Cancer·S O KrollsR C Boyers
Apr 1, 1997·The Journal of Laryngology and Otology·S A Kamal, E O Othman
Mar 17, 1999·The American Journal of Surgical Pathology·M BrandweinL Granowetter
Jan 8, 2000·Journal of Pediatric Surgery·A Alvarez-MendozaD Carrasco-Daza
Jul 13, 2000·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·R S GreenP Argani
Dec 17, 2003·Acta Cytologica·Ruoqing Huang, Shabnam Jaffer
Jul 28, 2004·Pediatric Radiology·Ensar YekelerGulden Acunas

❮ Previous
Next ❯

Citations

Jul 20, 2011·Rare Tumors·Kanwal M FarooqiDeepa Manwani
Oct 29, 2013·National Journal of Maxillofacial Surgery·Kanaram ChoudharySatish Krishanan
Jan 6, 2011·Fetal and Pediatric Pathology·Yasi SaffariM Alba Greco
Jun 18, 2010·International Journal of Pediatric Otorhinolaryngology·M PrigentD Orbach
May 13, 2008·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·D D MarucciD J Dunaway
Jan 22, 2009·Pediatric Blood & Cancer·D K StonesD Griessel
Aug 25, 2010·Pediatric Blood & Cancer·Xiao-Feng ShanGuang-Yan Yu
Jun 29, 2010·Pediatric Blood & Cancer·Ebru Tugrul SaribeyogluBilge Bilgic
Jul 28, 2015·Diagnostic Cytopathology·Sant Prakash KatariaNitin Garg
Jul 3, 2016·International Journal of Pediatric Otorhinolaryngology·Alexandria L IraceReza Rahbar
Nov 3, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Irving DardickR John McComb
Dec 17, 2009·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Deepa T Patil, Pauline M Chou

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.