Treatment of metronidazole-resistant Trichomonas vaginalis

Sexual Health
Linda M GoldmanAndrea Rapkin

Abstract

A 58-year-old Caucasian woman presented with a 14-month history of persistent trichomoniasis not responsive to numerous courses of metronidazole and tinidazole. Vaginal secretion samples were obtained for sensitivity testing and treatment recommendations. In vitro susceptibility testing revealed the patient's Trichomonas vaginalis isolate was highly resistant to both metronidazole and tinidazole. She was treated with topical furazolidone and experienced a complete symptomatic cure and culture remained negative 35 days post furazolidone treatment.

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Citations

Sep 17, 2011·Current Infectious Disease Reports·Megan R Miller, Paul Nyirjesy
Feb 23, 2013·Infection and Immunity·Gila LustigPatricia J Johnson
Apr 2, 2013·Sexually Transmitted Infections·Christina A Muzny, Jane R Schwebke
Feb 22, 2014·Expert Review of Anti-infective Therapy·Arlene C SeñaMarcia M Hobbs
Nov 22, 2013·Molecular Microbiology·David LeitschMichael Duchêne
Feb 24, 2015·International Journal of Antimicrobial Agents·Markus KranzlerJulia Walochnik
Aug 6, 2015·BMC Infectious Diseases·Patricia Kissinger
Dec 12, 2012·Trends in Parasitology·Melissa D ConradJane M Carlton
Dec 24, 2010·FEMS Microbiology Letters·Ivone de Andrade RosaMarlene Benchimol
Mar 13, 2014·International Journal of STD & AIDS·Jackie SherrardAnn Sullivan
Sep 22, 2011·Sexually Transmitted Diseases·Paul NyirjesyLaura J Mulcahy
Feb 27, 2016·F1000Research·David Leitsch
Feb 15, 2018·Antimicrobial Agents and Chemotherapy·Arindam P GhoshJane R Schwebke

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