Treatment of multidrug-resistant tuberculosis in Indonesia

Chemotherapy
M HadiartoA Hudoyo

Abstract

There is growing concern, even among developed countries, about the increasing incidence of multidrug-resistant tuberculosis (MDR-TB). Results are reported from a study investigating ofloxacin used in the treatment of 57 patients with MDR-TB. Patients received ofloxacin 400 mg/day as well as three other sensitive anti-TB drugs based on susceptibility tests. Treatment duration was 9 months. Preliminary results of 35 evaluable patients show 55% of MDR-TB cases converted to smear and culture negative within 3 months of therapy. Ofloxacin in combination with other sensitive anti-TB medication shows promise in the treatment of MDR-TB and further studies are recommended.

Citations

Jan 10, 2003·The New England Journal of Medicine·Carole MitnickPaul Farmer
Jun 13, 2008·Biomedical Engineering Online·Gari D CliffordHamish Sf Fraser
Jun 5, 2002·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ann S G LeeSin Yew Wong
Sep 27, 2005·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Seyed Mehdi MirsaeidiAli Akbar Velayati
Jun 2, 2012·Asia-Pacific Journal of Public Health·Sampurna KakchapatiChamnein Choonpradub
Jan 20, 2004·Tropical Medicine & International Health : TM & IH·Richard J Coker

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