PMID: 11924446Apr 2, 2002Paper

Treatment of newly diagnosed epileptic crises. A French experience

Revue neurologique
Groupe CAROLE (Coordination Active du Réseau Observatoire Longitudinal de l'Epilepsie)

Abstract

CAROLE is a prospective survey of 1942 children and adults presenting at least one unprovoked epileptic seizure first diagnosed between May 1 1995 and June 30 1996 by 243 French neurologists and neuropediatricians. In half these cases, the patient had already experienced more than one seizure at the time of diagnosis. Patients presenting only one seizure but either a case history or significant EEG or neuroimaging abnormalities suggestive of a high risk of recurrence were classified as cases of epilepsy. Drug treatment was prescribed to 73 p. 100 of the cohort. Treatment was far more frequent in cases where seizure had recurred (90 p. 100) than in cases of first seizure (54 p. 100) (p < 0.0001). In the latter category, the older the patients, the more likely they were to be treated (69 p. 100 of patients > or = 60 years old versus 49 p. 100 of those under 24 years of age, p = 0.001). Those with multiple onset were more often treated than those with single onset (48 p. 100 of cases of single seizure versus 80 p. 100 of clustered seizures and 90 p. 100 of status epilepticus, p < 0.0001), as were cases of complex partial seizure (68 p. 100 versus just under 50 p. 100 of cases of generalized seizure, p = 0.0001), those with epilept...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.