PMID: 6969442Nov 1, 1980Paper

Treatment of otitis media with cefaclor, a new oral cephalosporin

Southern Medical Journal
G H Aronovitz

Abstract

Cefaclor, a new semisynthetic cephalosporin, was evaluated for efficacy in the treatment of otitis media in 46 pediatric patients who had aspiration of the middle ear for culture. The dose of cefaclor ranged from 29 to 42 mg/kg/day administered in three divided doses. No organism was isolated in nine of the 46 patients. Streptococcus pneumoniae was isolated in 43% and Hemophilus influenzae in 27% of the remainder. A bacteriologic cure was achieved in 97% of cases with culturable organisms. The one treatment failure was due to a cefaclor-resistant strain of H influenzae. The medication was well tolerated with the exception of one case of eosinophilia that was possibly drug related. Cefaclor given three times a day is an effective program for the treatment of otitis media.

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.