Treatment of Prosthetic Joint Infection with Debridement, Antibiotics and Irrigation with Implant Retention - a Narrative Review

Journal of Bone and Joint Infection
Ricardo Sousa, Miguel Araújo Abreu

Abstract

Prosthetic joint infection usually requires combined medical and surgical therapy. While revision surgery is widely considered to be the gold standard surgical procedure, debridement, antibiotics and irrigation with implant retention is a very appealing alternative. There is however great controversy regarding its real worth with success rates ranging from 0% to over 90%. A number of different patient and host related variables as well as specific aspects of surgical and medical management have been described as relevant for the final outcome. Along this paper, the authors will provide the readers with a critical narrative review of the currently available literature while trying to provide concise and practical treatment recommendations regarding adequate patient selection criteria, proper surgical technique and optimal antibiotic therapy.

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Citations

Oct 15, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Álvaro AuñónJohn-Jairo Aguilera-Correa
Feb 12, 2020·Surgical Infections·Ellis BernsDioscaris R Garcia
Jul 1, 2020·The Bone & Joint Journal·Noam ShohatUNKNOWN ESCMID Study Group of Implant Associated Infections (ESGIAI) and the Northern Infection Network of Joint Arthroplasty (NINJA
Jul 11, 2020·JBJS Case Connector·Taylor PaziukRobert Good
Nov 24, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Dioscaris GarciaChristopher T Born
Dec 8, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Nicole PrinceJonathan W Boyd
Mar 7, 2021·Journal of Clinical Medicine·Nike WalterVolker Alt
Mar 31, 2021·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·P TatarelliM Bassetti
Nov 9, 2021·Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews·Stuart IrwinSimon Swift

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Methods Mentioned

BETA
lavage

Software Mentioned

DAIR

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Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

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