Treatment of ragweed allergic conjunctivitis with cromolyn sodium 4% ophthalmic solution

American Journal of Ophthalmology
G A FridayS Rand

Abstract

We treated 31 patients with ragweed conjunctivitis in an eight-week, double-masked parallel-group study with cromolyn sodium 4% ophthalmic solution. Analysis of data showed preseason serum IgE antibody to ragweed level was a significant predictor of drug response. Of 16 patients with ragweed IgE values of less than 100 ng/ml, the nine treated with cromolyn had significantly fewer symptoms during the course of treatment than the seven in the placebo group. Of the 15 remaining patients, who had IgE levels of more than 100 ng/ml, the eight treated with cromolyn improved but the difference between their symptom scores and those of the seven patients treated with placebo was not statistically significant.

References

Aug 1, 1978·Annals of Internal Medicine·I L Bernstein, C L Johnson
Feb 1, 1979·International Ophthalmology·L Hyvärinen
Mar 1, 1977·The Journal of Allergy and Clinical Immunology·N I HandelmanD L Miller
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Dec 1, 1973·Clinical Allergy·N S Rice, B R Jones
Mar 1, 1982·Archives of Ophthalmology·H B Ostler

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Citations

Jan 1, 1986·Survey of Ophthalmology·M R Allansmith, R N Ross
Jul 1, 1993·Survey of Ophthalmology·M B Abelson, K Schaefer
Jul 1, 1994·The Journal of Allergy and Clinical Immunology·E F JuniperD R King
Oct 1, 1992·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M LeinoE Takalo
May 9, 2002·Expert Opinion on Pharmacotherapy·Leonard Bielory
May 1, 1985·Pharmacotherapy·G G Shapiro, P König

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