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Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha

Arthritis and Rheumatism

Dec 1, 1993

M J ElliottJ Ghrayeb

Abstract

To evaluate the safety and efficacy of a chimeric monoclonal antibody to tumor necrosis factor alpha (TNF alpha) in the treatment of patients with rheumatoid arthritis (RA). Twenty patients with active RA were treated with 20 mg/kg of anti-TNF alpha in an open phase I/II trial lasting 8...read more

Mentioned in this Paper

Monoclonal Antibodies
Necrosis
Tumor Necrosis Factor-alpha
Chimera Organism
TNF
Dose-Response Relationship, Immunologic
Rheumatoid Arthritis
Cytokine
IL6
Immunotherapy
1
89
1
Paper Details
References
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  • Citations452
1
  • References5
  • Citations452
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Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha

Arthritis and Rheumatism

Dec 1, 1993

M J ElliottJ Ghrayeb

PMID: 8250987

DOI: 10.1002/art.1780361206

Abstract

To evaluate the safety and efficacy of a chimeric monoclonal antibody to tumor necrosis factor alpha (TNF alpha) in the treatment of patients with rheumatoid arthritis (RA). Twenty patients with active RA were treated with 20 mg/kg of anti-TNF alpha in an open phase I/II trial lasting 8...read more

Mentioned in this Paper

Monoclonal Antibodies
Necrosis
Tumor Necrosis Factor-alpha
Chimera Organism
TNF
Dose-Response Relationship, Immunologic
Rheumatoid Arthritis
Cytokine
IL6
Immunotherapy
1
89
1

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Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

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References
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