PMID: 6170656Nov 1, 1981Paper

Treatment of scabies and pediculosis with lindane preparations: an evaluation

Journal of the American Academy of Dermatology
B Shacter

Abstract

Risks and benefits involved in the use of lindane preparations for the treatment of scabies and head louse infestations are evaluated. Although lindane per si is moderately toxic, capable of inducing neurotoxic and hemotoxic effects, there is little evidence that the preparations used in the treatment of scabies and pediculosis give rise to toxic symptoms when applied according to directions. Current evidence does not support the view that lindane is intrinsically carcinogenic, although very high doses have induced hepatomas in mice. It is concluded that the benefits obtained in the use of lindane as a scabicide and pediculicide outweigh risks involved in its use for these purposes. Comparison with other preparations available for the control of scabies and pediculosis indicate that lindane is probably the most effective scabicide, although it also shows the greatest toxic potential. Malathion and pyrethrin preparations seem equally effective against head lice. Suggestions for even safer use of lindane are discussed.

References

Mar 1, 1977·Archives of Dermatology·L M SolomonD P West
Apr 1, 1977·The Journal of Parasitology·G F SlonkaM G Schultz
Apr 3, 1959·Science·J R FOUTS, R H ADAMSON
Nov 1, 1950·A.M.A. Archives of Dermatology and Syphilology·L K HALPERNR S WEISS
Mar 1, 1950·Archives of Dermatology and Syphilology·L V KORNBLEE, F C COMBES

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Citations

Jan 1, 1984·Archives of Dermatological Research·E MenczelR Wester
Mar 1, 1997·Lippincott's Primary Care Practice·K G Pigott
Oct 27, 2004·Annales de dermatologie et de vénéréologie·S MostinckxM de la Brassinne
May 1, 1990·International Journal of Dermatology·B F O'DonnellF C Powell
Jul 1, 1984·Pediatric Dermatology·J E Rasmussen
Jul 24, 2001·Drugs·T C RoosD R Bickers
Dec 1, 1991·Journal of the American Academy of Dermatology·R S Purvis, S K Tyring
Jan 1, 1983·Journal of the American Academy of Dermatology·M K Polano
May 9, 2006·Dermatologic Clinics·Sancy A Leachman, Barbara R Reed
Sep 1, 1987·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·M Sanford-Driscoll
Jul 1, 1983·International Journal of Dermatology·L C ParishR Schwartzman
Jun 30, 2015·Indian Journal of Dermatology·Prashant Verma, Chaitanya Namdeo
Aug 1, 1991·The British Journal of Dermatology·D A Burns
Feb 24, 2005·Contact Dermatitis·Ke-Jen YuHsin-Chun Ho
Aug 1, 1984·The Australasian Journal of Dermatology·J E Rasmussen
Dec 1, 1982·Journal of American College Health : J of ACH·N J Fiumara, S Mason
May 1, 1983·Postgraduate Medicine·R J Caserio
Apr 30, 1983·The Medical Journal of Australia·C A Commens

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