Treatment of solar lentigines

Journal of the American Academy of Dermatology
Jean-Paul OrtonneDoris Hexsel

Abstract

Therapy for solar lentigines is diverse but can be divided into two broad categories: physical therapy and topical therapy. Physical therapies are frequently used with excellent clinical success rates, but this has to be balanced against associated side effects and recurrence rates with certain therapies. A range of topical therapies have been used and, more recently, fixed combinations of topical agents have been investigated. The Pigmentary Disorders Academy undertook to evaluate the clinical efficacy of the different treatments of solar lentigines in order to generate a consensus statement on their management. Clinical papers published during the past 20 years were identified through MEDLINE searches and methodology and outcome were assessed according to guidelines adapted from the US Preventive Services Task Force (USPSTF) on health care. The consensus of the group was that first-line therapy for solar lentigines was ablative therapy with cryotherapy. Although no large-scale studies have been completed, there is also good evidence to suggest that lasers are an effective treatment. An alternative to ablative therapy is topical therapy and there is good evidence to support the use of a fixed double combination, as well as ret...Continue Reading

References

Aug 1, 1979·Cryobiology·A A GageG W Greene
Feb 6, 1992·The New England Journal of Medicine·E S RafalJ J Voorhees
Jan 23, 1991·Biochimica Et Biophysica Acta·A PalumboG Prota
May 1, 1991·Archives of Dermatology·G D WeinsteinE G Thorne
Apr 1, 1990·The British Journal of Dermatology·J P Ortonne
Sep 1, 1989·The Journal of Dermatologic Surgery and Oncology·P S Collins
Sep 1, 1989·The Journal of Dermatologic Surgery and Oncology·G D Monheit
Jun 1, 1994·Journal of the American Academy of Dermatology·R S SternK A Arndt
May 1, 1996·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·N NewmanR L Moy
Jan 1, 1997·Dermatology : International Journal for Clinical and Investigative Dermatology·D KoperaM Landthaler
Apr 8, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Y T Li, K C Yang
Dec 22, 1999·Acta Dermato-venereologica·C C ZouboulisC E Orfanos
Mar 21, 2000·Plastic and Reconstructive Surgery·K YoshimuraT Iga
May 18, 2000·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·D M HexselD O Gobbato
Jul 25, 2000·The British Journal of Dermatology·B Almond-Roesler, C C Zouboulis
Jul 13, 2000·Archives of Dermatology·A J StratigosK A Arndt
Aug 12, 2000·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·H H ChanT Kono
Nov 30, 2000·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·K K Cook, W R Cook
Apr 10, 2002·Archives of Dermatology·Alan RosenbachRobert H Johr
Jun 26, 2002·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Akira KawadaTadashi Tezuka
Jun 29, 2002·Journal of Dermatological Science·Akira KawadaKouji Iwakiri
Nov 20, 2002·Archives of Dermatology·Tania J PhillipsUNKNOWN Tazarotene Cream Photodamage Clinical Study Group
Mar 8, 2003·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·T RashidT S Haroon
Mar 27, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Claudia CotellessaSergio Chimenti
Jul 2, 2003·Journal of the American Academy of Dermatology·Sewon KangChristopher E M Griffiths
Aug 28, 2003·Journal of the European Academy of Dermatology and Venereology : JEADV·L Petit, G E Piérard
Oct 3, 2003·International Journal of Dermatology·Alexander Lugo-JanerJorge L Sanchez

❮ Previous
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Citations

Sep 19, 2008·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Afshin SadighhaGolnaz Muhaghegh-Zahed
Aug 13, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Myra O VillarealHiroko Isoda
Nov 26, 2009·Expert Opinion on Drug Metabolism & Toxicology·Gérald E PiérardPascale Quatresooz
Feb 2, 2013·Facial Plastic Surgery Clinics of North America·Marty O VisscherW John Kitzmiller
Apr 21, 2016·Lasers in Surgery and Medicine·Vasanop VachiramonKumutnart Chanprapaph
Feb 13, 2016·Journal of Cutaneous and Aesthetic Surgery·Brian Wei Cheng Anthony Tian
Jan 1, 2008·Drug Discovery Today. Disease Mechanisms·Michaela Brenner, Vincent J Hearing
Jul 31, 2007·Facial Plastic Surgery Clinics of North America·Siegrid S YuRoy C Grekin
Feb 12, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·S Vano-GalvanP Jaén
Feb 16, 2012·Lasers in Surgery and Medicine·Kelly StankiewiczMathew Avram
Apr 19, 2013·The Journal of Dermatology·Tessin WatanabeOsamu Yamamoto
Apr 2, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·D HexselC Siega
Aug 1, 2014·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·E QuestelG Josse
Jan 15, 2014·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Hee Jin JunHei Sung Kim
Aug 1, 2006·Photomedicine and Laser Surgery
Jun 12, 2008·Journal of Cutaneous Medicine and Surgery·Alberto GoldmanFlávia Rossato
Jun 12, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·S GuidaF Farnetani
Mar 6, 2018·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Punyaphat Sirithanabadeekul, Rattima Srieakpanit
May 5, 2010·Plastic and Reconstructive Surgery·Erica H LeeJoseph J Disa
Mar 16, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·T PasseronA Badawi
May 31, 2017·Lasers in Surgery and Medicine·Brian P HiblerKishwer S Nehal
Dec 13, 2016·American Journal of Clinical Dermatology·Neelam A VashiRoopal V Kundu
Sep 13, 2018·International Journal of Molecular Sciences·Sandra Del BinoFrançoise Bernerd
Jan 15, 2019·Drugs & Aging·Andrew M ArmentaAmmar M Ahmed
Mar 18, 2015·Experimental Dermatology·Motoki NakamuraJean Krutmann
Jan 27, 2019·Lasers in Surgery and Medicine·Daniel P Friedmann, Jennifer D Peterson
May 23, 2019·Lasers in Surgery and Medicine·Mandy W M ChanHenry Hin-Lee Chan
Nov 18, 2020·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Sorina DanescuK Fritz
May 18, 2021·Pigment Cell & Melanoma Research·Avni Nautiyal, Sarika Wairkar
Aug 18, 2021·Lasers in Surgery and Medicine·Arielle N B KauvarKevin Schomacker

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