Treatment of status asthmaticus--hormone changes before and after aminophylline i.v. drip therapy

Acta Paediatrica Japonica; Overseas Edition
Y IikuraA Sasamoto

Abstract

The treatment of status asthmaticus is one of the most important factors in controlling the patient with asthma attacks. We have studied hormone changes in status asthmaticus and considered what is the best treatment in the asthma attack condition in children. Antidiuretic hormone (ADH), renin activity, and aldosterone activity are elevated in severe asthma attack conditions, and these high levels are correlated with high levels in Wood's clinical score. It is theoretical that patients with dehydration and respiratory failure show such elevation in hormones, and it is well known that under such conditions beta 2-stimulant enhances renin production. From our study, it is concluded that beta 2-stimulant subcutaneous injection must be considered in status asthmaticus. In children, aminophylline i.v. drip therapy may be one of the best treatments in status asthmaticus.

References

Jan 14, 1971·The New England Journal of Medicine·P N WeissmanR I Gregerman
Dec 16, 1947·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·E B VERNEY

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Citations

Jun 1, 1994·Journal of Clinical Epidemiology·D A van der WindtA J Veerman
Oct 5, 2017·Expert Review of Respiratory Medicine·Antonio José Justicia-GrandeFederico Martinón-Torres

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