Treatment of stress urinary incontinence using polyacrylamide hydrogel in women after radiotherapy: 1-year follow-up

International Urogynecology Journal
Jan KrhutPeter Zvara

Abstract

Information on urethral bulking therapy in women after previous pelvic radiotherapy is lacking. This study compared the safety and efficacy of polyacrylamide intraurethral injections in patients with and without previous radiotherapy. A total of 46 patients with severe stress urinary incontinence (SUI) were enrolled in this multicenter prospective trial. Group A consisted of 24 patients with previous radiotherapy to the pelvis for the treatment of a gynaecological malignancy. Group B consisted of 22 patients without previous radiotherapy. All patients were treated with a transurethral injection of a bulking solution (Bulkamid). The average follow-up was 12.4 months. The paired Wilcoxon test was used to compare the results before and after the procedure within the groups, and the two-sample Wilcoxon test was used for comparisons between groups. Complete continence was achieved in 25 % of patients in group A and in 36.4 % of patients in group B. Significantly reduced urine leakage was observed in both groups (p = 0.0164 in group A and p = 0.0002 in group B). The total scores in the International Consultation on Incontinence Questionnaire decreased by 5.2 in group A (p = 0.0000) and 6.36 in group B (p = 0.0001). The scores for the...Continue Reading

References

Jan 1, 1997·International Urogynecology Journal and Pelvic Floor Dysfunction·S Herschorn, S B Radomski
Apr 12, 2002·Neurourology and Urodynamics·Werner SchäferUNKNOWN International Continence Society
Jul 1, 2004·Neurourology and Urodynamics·Kerry AveryPaul Abrams
Oct 3, 2008·Urology·R Duane Cespedes, Faye B Serkin
Nov 6, 2008·International Urogynecology Journal and Pelvic Floor Dysfunction·E A EreksonD L Myers
Mar 10, 2009·International Urogynecology Journal and Pelvic Floor Dysfunction·Maurizio SeratiPierFrancesco Bolis
Oct 12, 2010·International Urogynecology Journal·Gerda TrutnovskyVesna Bjelic-Radisic
Nov 17, 2011·International Urogynecology Journal·Danielle Markle Price, Karen Noblett
Jun 19, 2012·International Urogynecology Journal·Stefan MohrAnnette Kuhn
Mar 20, 2014·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Carlo Vecchioli-Scaldazza Vecchioli-ScaldazzaVincenzo Ferrara
May 8, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Alois MartanJan Krhut

❮ Previous
Next ❯

Citations

Oct 13, 2018·Neurourology and Urodynamics·Amy D Dobberfuhl
May 9, 2019·Neurourology and Urodynamics·Ervin KocjancicÖmer Acar
Jan 21, 2017·Female Pelvic Medicine & Reconstructive Surgery·Daniel AltmanHelena Kopp Kallner
Oct 19, 2019·BJU International·Rachael D SussmanBenjamin M Brucker
Apr 19, 2017·International Urogynecology Journal·Stefan MohrAnnette Kuhn
Feb 22, 2017·International Urogynecology Journal·Zain A SiddiquiShahzad Shah
Jan 8, 2021·Neurourology and Urodynamics·Torsten BroscheEric R Sokol
May 21, 2021·Neurourology and Urodynamics·Venetia HoeHelen E O'Connell

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.