Treatment of synchronous peritoneal carcinomatosis and liver metastases from colorectal cancer

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Dominique EliasP Lasser

Abstract

To report our experience of peritoneal carcinomatosis (PC) discovered during abdominal exploration in patients with liver metastases (LM). Liver resection plus cytoreductive surgery were combined in 24 patients with LM and moderate PC from colorectal origin treated with a curative intent between January 1993 and November 2003. The mean operative time was 357+/-112 min and median blood loss was 719 ml. One postoperative death occurred and postoperative morbidity was 58%. The mean hospital stay was 21.4+/-4.2 days. Three-year overall and disease-free survival rates were respectively 41.5% (confidence interval [CI]: 23-63) and 23.6% (CI: 11-45). Seven patients are disease-free with a mean follow-up of 27.8 months after their last surgery, 3 having a repeated hepatectomy. Three patients developed a peritoneal recurrence and 13 had recurrence in the liver. The only significant prognostic factor was a number of LMs of less than 3 (p < 0.01). A combined treatment of LM plus PC is feasible and is beneficial in selected patients presenting three or fewer metastases.

References

Jan 1, 1989·Seminars in Surgical Oncology·R E Pollock, J A Roth
Apr 1, 1995·Archives of Surgery·E HansenK Taeger
Aug 1, 1996·Hematology/oncology Clinics of North America·D Y Kavanaugh, D P Carbone
Oct 2, 2001·The British Journal of Surgery·G TsavellasT G Allen-Mersh
May 8, 2003·The British Journal of Surgery·D EliasP Lasser
Oct 11, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Vic J VerwaalFrans A N Zoetmulder
Apr 6, 2004·The Surgical Clinics of North America·Dominique EliasMichel Ducreux
Apr 6, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C P CarmignaniP H Sugarbaker
Apr 28, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D EliasP Lasser
Aug 18, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·O GlehenP Rat

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Citations

Feb 13, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Bolanle AsiyanbolaTimothy M Pawlik
Apr 16, 2011·Journal of Gastrointestinal Cancer·Terence C Chua, David L Morris
May 4, 2011·Revista da Associação Médica Brasileira·Felipe José Fernández CoimbraHéber Salvador de Castro Ribeiro
Jun 27, 2009·The Cancer Journal·Santiago González-MorenoConcepción González-Hernando
Jun 27, 2009·The Cancer Journal·Pompiliu PisoHans Juergen Schlitt
Feb 9, 2012·International Journal of Surgical Oncology·Anton L GueorguievSteven C Cunningham
Jun 26, 2009·Annals of Surgical Oncology·Darren R Carpizo, Michael D'Angelica
Mar 20, 2010·World Journal of Gastroenterology : WJG·Bernardino RamponeGiuseppe Confuorto
Nov 1, 2011·World Journal of Gastroenterology : WJG·Evangelos P MisiakosGregory Kouraklis
May 31, 2014·World Journal of Gastroenterology : WJG·Özgür AkgülMesut Tez
Jan 7, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·L GraziosiA Donini
Jun 7, 2013·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·F LosaE Aranda
Jun 12, 2014·International Journal of Colorectal Disease·Carlo VallicelliGiorgio M Verdecchia
Apr 23, 2009·World Journal of Surgery·Vanessa M BanzDaniel Candinas
Jul 29, 2011·Journal of Cancer Research and Clinical Oncology·Jianmin XuUNKNOWN Committee of Colorectal Cancer, Chinese Anti-cancer Association
Feb 13, 2016·Critical Reviews in Oncology/hematology·Dario BarattiMarcello Deraco
Apr 12, 2016·Indian Journal of Surgical Oncology·Sanket S MehtaOlivier Glehen
Mar 29, 2016·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·William J HaddenThomas J Hugh
Jan 26, 2016·Journal of Surgical Oncology·Yaniv BergerDaniel M Labow
Jul 3, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S RissB Moran
Jul 13, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M A AllardD Castaing
Oct 2, 2012·Surgical Oncology Clinics of North America·Dominique EliasDiane Goéré
Jun 7, 2011·Surgical Oncology Clinics of North America·Kwan N LauDavid A Iannitti
Jul 20, 2010·The Surgical Clinics of North America·David SindramDavid A Iannitti
Jul 8, 2010·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·L Maggiori, D Elias
Aug 4, 2009·The Lancet Oncology·Darren R Carpizo, Michael D'Angelica
Jul 28, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·T C ChuaD L Morris
May 20, 2008·Surgical Oncology Clinics of North America·Daniel Jaeck, Patrick Pessaux
Feb 8, 2008·Surgical Oncology·G ConfuortoC Viviano
Nov 17, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Y S Chun, J N Vauthey
Jun 5, 2007·Surgical Oncology·R LochanD M Manas
Aug 22, 2009·Journal of Surgical Oncology·Santiago González-MorenoLuis González-Bayón
Aug 30, 2008·Journal of Surgical Oncology·Vic J VerwaalMarcello Deraco
Aug 29, 2014·Journal of Surgical Oncology·Shuja AhmedEdward A Levine
Jul 4, 2007·Surgical Oncology Clinics of North America·Daniel JaeckEdoardo Rosso
Aug 13, 2015·World Journal of Surgical Oncology·Diego VicenteAlexander Stojadinovic

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