PMID: 7087145Jul 23, 1982Paper

Treatment of tic douloureux by percutaneous retrogasserian glycerol injection

JAMA : the Journal of the American Medical Association
L Dade Lunsford

Abstract

Thirty patients with tic douloureux underwent treatment by percutaneous retrogasserian glycerol injection (PRGI). All patients had symptomatic trigeminal neuralgia refractory to medical therapy. Fifteen patients had recurrent tic after one to four prior operations. The technique was simple to perform and required no intraoperative physiological testing or short-acting barbiturate supplementation during transovale placement of a spinal needle in the trigeminal cistern of Meckel's cave. Precise placement of small volumes (0.15 to 0.35 mL) of sterile glycerol was ensured by first demonstrating the anatomy of the trigeminal cistern using metrizamide. Overall, 23 patients have remained pain free five to 12 months after treatment. Nineteen patients had no change in facial sensation after injection. Treatment by PRGI is a valid alternative therapy for tic douloureux, with the additional benefit of a much-reduced incidence of facial sensory loss when compared with differential thermal rhizotomy by a radiofrequency-induced lesion technique. Facial deafferentation is not mandatory for successful percutaneous treatment of tic douloureux.

Citations

Aug 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·B Mittal, D G Thomas
Apr 16, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·T L al-Khateeb
Jun 1, 1988·Muscle & Nerve·J M VallatJ J Moreau
Nov 26, 2010·Neurosurgery·Hideyuki KanoL Dade Lunsford
May 15, 2017·Stereotactic and Functional Neurosurgery·Jonathan CohenL Dade Lunsford
Aug 1, 2006·Surgical Neurology·Alessandra GorgulhoMichael T Selch
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Sep 1, 1983·JPEN. Journal of Parenteral and Enteral Nutrition·R C TaoF Benjamin
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Jan 17, 2014·Journal of Maxillofacial and Oral Surgery·Monika ParmarPurushotham Naidu

Related Concepts

Glycerin
Injectables
Metrizamide
Preoperative Procedure
Relapse
Calvaria
Secondary Trigeminal Neuralgia

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