Treatment of tobacco use disorders in smokers with serious mental illness: toward clinical best practices

Harvard Review of Psychiatry
A Eden EvinsAlexandra Laffer

Abstract

Addiction to tobacco-derived nicotine remains highly prevalent in the United States, with 18% using daily, and 53% of those with serious mental illness using daily. While smokers with serious mental illness have been excluded from most large nicotine-dependence treatment studies, a growing evidence base is available to guide clinicians in assisting their patients with psychiatric illness to quit smoking. The aim of this review is to present the evidence on safety and efficacy of smoking cessation interventions for those with serious mental illness. Smokers with schizophrenia spectrum disorders should receive varenicline or bupropion with or without nicotine replacement therapy in combination with behavioral treatment. Although more research is needed, preliminary evidence suggests that varenicline in combination with behavioral support is efficacious and well tolerated for smoking cessation for those with bipolar disorder and major depressive disorder. Controlled trials have found no evidence that in patients with serious mental illness, the use of pharmacotherapeutic cessation aids worsens psychiatric symptoms or increases the rate of psychiatric adverse events. Converging evidence indicates that a majority of smokers with ser...Continue Reading

References

Jul 1, 1990·Comprehensive Psychiatry·L S CoveyF Stetner
Sep 26, 1990·JAMA : the Journal of the American Medical Association·A H GlassmanJ Johnson
Feb 1, 1997·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·J AddingtonD Hodgins
Mar 27, 1998·European Journal of Clinical Pharmacology·D SchrenkM Eichelbaum
Jul 31, 1999·Clinical Pharmacokinetics·S Zevin, N L Benowitz
Mar 4, 2000·The American Journal of Psychiatry·J Y TsohS M Hall
Oct 21, 2000·The British Journal of Psychiatry : the Journal of Mental Science·S BrownB Barraclough
Nov 22, 2000·JAMA : the Journal of the American Medical Association·K LasserD H Bor
Nov 6, 2001·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·A E EvinsD C Goff
Jun 25, 2002·Biological Psychiatry·Tony P GeorgeThomas R Kosten
Jun 27, 2002·Schizophrenia Research·Jose de LeonLori Dinsmore
Feb 13, 2003·Archives of General Psychiatry·Ronald C KesslerAlan M Zaslavsky
Mar 12, 2003·Addictive Behaviors·Joel D KillenAnn Varady
Mar 11, 2004·JAMA : the Journal of the American Medical Association·Ali H MokdadJulie L Gerberding
Oct 30, 2004·The American Journal of Psychiatry·Sharon M HallJennifer Cullen
Feb 12, 2005·The Journal of Clinical Psychiatry·Donald C GoffFrank M Sacks
May 7, 2005·Journal of Clinical Psychopharmacology·A Eden EvinsNancy A Rigotti
Sep 30, 2006·American Journal of Public Health·Sharon M HallJulie A Gorecki
Nov 1, 2006·The American Journal of Psychiatry·Amanda BakerKay Wilhelm
Jun 30, 2007·American Journal of Public Health·Judith J ProchaskaJulie A Gorecki
Sep 17, 2008·Journal of Clinical Psychopharmacology·Andrea H WeinbergerTony P George
Nov 4, 2009·Archives of General Psychiatry·Megan E PiperTimothy B Baker
Dec 4, 2009·Schizophrenia Bulletin·Robert W BuchananUNKNOWN Schizophrenia Patient Outcomes Research Team (PORT)
Dec 17, 2009·Annual Review of Public Health·Steven A Schroeder, Chad D Morris
Nov 1, 2011·Journal of General Internal Medicine·Jennifer M GierischJohn W Williams
Jun 28, 2012·Journal of Dual Diagnosis·Tony P GeorgeAndrea H Weinberger
Sep 11, 2012·Journal of Dual Diagnosis·Becky S WuTony P George

❮ Previous
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Citations

Dec 5, 2015·Frontiers in Molecular Neuroscience·Tasnim S MohamedAyman K Hamouda
Jan 20, 2016·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Alana M RojewskiUNKNOWN Comorbidities Workgroup of the Society for Research on Nicotine and Tobacco (SRNT) Treatment Network
Feb 24, 2016·Journal of Addiction Medicine·Joseph R DiFranzaJonathan Winickoff
Sep 11, 2016·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Arthur L BrodyCharles McCreary
May 11, 2017·Journal of Dual Diagnosis·Aline Rodrigues LoretoJoão Maurício Castaldelli-Maia
Sep 19, 2017·The International Journal of Social Psychiatry·João Mauricio Castaldelli-MaiaJ Taylor Hays
Oct 24, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Mary F BrunetteGregory J McHugo
Apr 16, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kelly E IrwinLori Wirth
Dec 13, 2017·Journal of Clinical Psychopharmacology·Maher Karam-HagePaul M Cinciripini
Feb 11, 2020·JMIR Mental Health·Mary F BrunetteHaiyi Xie
Jan 21, 2020·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Sandra J JapuntichScott E Sherman
Sep 3, 2020·European Archives of Psychiatry and Clinical Neuroscience·Marie VipreyGuillaume Fond
Dec 24, 2019·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Jennifer W TideyEric C Donny
Aug 5, 2017·Community Mental Health Journal·Clare MeernikAdam O Goldstein
Jun 4, 2020·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·João M Castaldelli-MaiaConstantine Vardavas
Apr 3, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·João Mauricio Castaldelli-MaiaDinesh Bhugra
Sep 15, 2019·Community Mental Health Journal·Sandra J JapuntichSteven S Fu
Feb 6, 2019·International Journal of Environmental Research and Public Health·Sharon LawnJames Stewart
Jan 29, 2019·Frontiers in Psychiatry·Hussien ElkholyLobna Azzam
Sep 19, 2020·International Journal of Methods in Psychiatric Research·Hamzah AlghzawiCarla Storr
Apr 29, 2020·The Journal of Behavioral Health Services & Research·Carol Carstens, Jessica Linley
Nov 4, 2020·Psychiatric Services : a Journal of the American Psychiatric Association·A Eden EvinsRobert M Anthenelli
Jun 26, 2021·Journal of Substance Abuse Treatment·João Mauricio Castaldelli-MaiaAntonio Ventriglio
Jul 21, 2021·Journal of Dual Diagnosis·Mark R HawesLeopoldo J Cabassa
Jul 30, 2021·Addiction Science & Clinical Practice·Young-Gyun SeoJaekyung Choi

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