Treatment of trigeminal neuralgia

Neurosurgery Clinics of North America
James K Liu, Ronald I Apfelbaum

Abstract

When medical treatment for trigeminal neuralgia fails or is limited by significant side effects, neurosurgeons need to inform their patients of all the available treatment options. The best treatment for the patient depends on the age of the patient, medical comorbidities, and the risks the patient is willing to assume. We recommend microvascular decompression for younger healthy patients with a longer life expectancy. Percutaneous trigeminal neurolysis remains a useful minimally invasive approach for the older patient and for the patient with medical comorbidities and a shorter life expectancy. The role of stereotactic radiosurgery in the treatment of trigeminal neuralgia will be better defined in the future. Partial sectioning of the trigeminal nerve may be considered in patients who have negative explorations during a microvascular decompression or when other less invasive procedures have failed to provide adequate relief.

References

Mar 1, 1976·Journal of Neurology, Neurosurgery, and Psychiatry·J E Court, C S Kase
Jul 1, 1988·Journal of Neurosurgery·R F Young
Apr 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·J M Zakrzewska, P N Patsalos
Apr 1, 1969·Headache·R H Sturman, F H O'Brien
Aug 1, 1966·Archives of Neurology·B W Rockliff, E H Davis
Jul 1, 1966·The American Journal of the Medical Sciences·A ChinitzA H Greenhouse
Dec 1, 1983·Journal of Neurosurgery·S Mullan, T Lichtor
Dec 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·S CanaveroP Benna
Apr 25, 1996·The New England Journal of Medicine·F G BarkerH D Jho
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·C L RogersB L Speiser
Jan 9, 2001·Journal of Neurosurgery·S MaesawaL D Lunsford
Aug 21, 2002·Journal of Neurosurgery·Bruce E PollockScott L Stafford

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Citations

Jul 17, 2008·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Francesco TomaselloFrancesco Maria Salpietro
Oct 7, 2009·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Paolo FerroliGiovanni Broggi
Sep 4, 2012·Journal of Maxillofacial and Oral Surgery·S M Agrawal, Deepashri H Kambalimath
Nov 3, 2005·Current Opinion in Ophthalmology·M Tariq Bhatti, Rachana Patel
Mar 12, 2009·The Neurologist·Sashank Prasad, Steven Galetta
Apr 22, 2009·European Journal of Medical Research·Jan VesperG Lammering
Jun 15, 2010·Journal of Neurosurgery·Marc S SchwartzFelipe Santos
Aug 21, 2013·Journal of Neurosurgery·Nan-Xiang Xiong, Hong-Yang Zhao
May 26, 2005·Neurosurgical Focus·Chad D ColeRonald I Apfelbaum
Mar 21, 2009·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Robert CerovicMargita Belusic Gobic
Jun 22, 2016·Neurosurgery Clinics of North America·Smruti K Patel, James K Liu
May 4, 2011·Arquivos de neuro-psiquiatria·Wuilker Knoner Campos, Marcelo N Linhares
Nov 5, 2014·Journal of Korean Neurosurgical Society·Chang Kyu ParkBong Arm Rhee
Feb 11, 2014·Neurosurgery·Jason S ChengNicholas M Barbaro
Aug 16, 2019·Journal of Neurosurgery·Gautam Mehta, Gregory Lekovic
Jul 17, 2021·Asian Journal of Neurosurgery·Mohamed Ragab Nagy, Bokhary Mahmoud

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