Treatment Options for Resistant Kawasaki Disease

Paediatric Drugs
Linny Kimly PhuongDavid Burgner

Abstract

"Resistant" Kawasaki disease is defined by the American Heart Association as failure to respond within 36 h following the first dose of intravenous immunoglobulin. The optimal management of resistant Kawasaki disease remains uncertain, the outcomes are potentially serious, and the cost of some treatments is considerable. We review the current evidence to guide treatment of resistant Kawasaki disease. Given the relative rarity, there are few trial data, and studies tend to be small and methodologically heterogeneous, making interpretation difficult and limiting generalisability. The literature on resistant Kawasaki disease should be interpreted with reference to current expert consensus guidelines.

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Citations

Oct 11, 2019·Current Opinion in Rheumatology·Francesca TirelliRolando Cimaz
Jul 5, 2019·Archives of Disease in Childhood·Linny K PhuongNigel Curtis
Apr 2, 2020·World Journal of Pediatrics : WJP·Shu WuJun-Bao Du
Aug 10, 2020·Journal of Paediatrics and Child Health·Coen ButtersDavid P Burgner
Sep 5, 2020·Paediatric Drugs·Giovanna FerraraRolando Cimaz
Jan 9, 2019·Frontiers in Immunology·Edoardo MarraniRolando Cimaz
Sep 22, 2020·Current Opinion in Pharmacology·Rui Long ZhangBetty Yuen-Kwan Law
Sep 15, 2020·Journal of Paediatrics and Child Health·Rakesh Kumar PilaniaSurjit Singh

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