Treatment outcomes of adult patients with recurrent tuberculosis in relation to HIV status in Zimbabwe: a retrospective record review.

BMC Public Health
Kudakwashe C TakarindaOwen Mugurungi

Abstract

Zimbabwe is a Southern African country with a high HIV-TB burden and is ranked 19th among the 22 Tuberculosis high burden countries worldwide. Recurrent TB is an important problem for TB control, yet there is limited information about treatment outcomes in relation to HIV status. This study was therefore conducted in Chitungwiza, a high density dormitory town outside the capital city, to determine in adults registered with recurrent TB how treatment outcomes were affected by type of recurrence and HIV status. Data were abstracted from the Chitungwiza district TB register for all 225 adult TB patients who had previously been on anti-TB treatment and who were registered as recurrent TB from January to December 2009. The Chi-square and Fischer's exact tests were used to establish associations between categorical variables. Multivariate relative risks for associations between the various TB treatment outcomes and HIV status, type of recurrent TB, sex and age were calculated using Poisson regression with robust error variance. Of 225 registered TB patients with recurrent TB, 159 (71%) were HIV tested, 135 (85%) were HIV-positive and 20 (15%) were known to be on antiretroviral treatment (ART). More females were HIV-tested (75/90, 83%...Continue Reading

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Citations

Aug 22, 2013·International Journal for Equity in Health·Bárbara Reis-SantosEthel L Maciel
Dec 12, 2012·Enfermedades infecciosas y microbiología clínica·Juan-Pablo MilletJoan A Caylà
Oct 10, 2012·Médecine et maladies infectieuses·G AgodokpessiM Gninafon
Jun 1, 2013·International Journal of Mycobacteriology·José Manuel RamosMiguel Górgolas
Nov 26, 2013·Revue des maladies respiratoires·G AgodokpessiM Gninafon
Apr 19, 2018·Tuberculosis Research and Treatment·Ato Kwamena TettehIrene Ayi
Jan 7, 2017·BMC Infectious Diseases·Rena MaimaitiRune Andersson

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