Treatment Outcomes of In-Office KTP Ablation of Vocal Fold Granulomas

The Annals of Otology, Rhinology, and Laryngology
Laura M DominguezC Blake Simpson

Abstract

To determine the effectiveness of in-office potassium-titanyl-phosphate (KTP) treatment of vocal fold granulomas and identify any predictors of complete lesion resolution. A retrospective review of patients who underwent in-office KTP ablation of vocal fold granulomas between 2007 and 2016 was performed. Medical records were reviewed for use of acid suppression medication, prior surgical treatment, voice therapy, laser settings, number of treatments, follow-up time, and Voice Handicap Index-10 (VHI-10) scores. Twenty-six patients underwent a total of 43 laser treatments. Eighty percent of patients were previously on acid suppression medication, and 42.3% had failed previous endoscopic treatments. Patients underwent a mean number of 1.65 ± 1.16 in-office treatments with decrease in size in 96.2% of cases. The VHI-10 was not significantly affected. Complete resolution occurred in 73.1% of cases with follow-up time ranging from 1 to 86 months (median = 9.5 months). No recurrences occurred in patients with complete resolution. Other than undergoing a single KTP treatment, no variable was found to be predictive of complete lesion resolution. Granuloma etiology was not predictive of lesion resolution but did correlate with symptom im...Continue Reading

References

Mar 1, 1994·The Journal of Laryngology and Otology·D J McFerranC B Croft
Jan 6, 2000·Journal of Voice : Official Journal of the Voice Foundation·A J EmamiD Bosch
Jan 5, 2002·Head & Neck·H T HoffmanT M McCulloch
Apr 14, 2005·The Annals of Otology, Rhinology, and Laryngology·Stephen B ClyneGregory N Postma
Feb 1, 2006·Brazilian Journal of Otorhinolaryngology·Elza Maria LemosDomingos H Tsuji
Jun 30, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jamie A KoufmanGregory N Postma
Nov 8, 2007·Current Opinion in Otolaryngology & Head and Neck Surgery·Steven M Zeitels, James A Burns
Mar 5, 2008·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Deng-Shan LinWan-Fu Su
Oct 27, 2009·The Laryngoscope·Clark A RosenGregory N Postma
Jul 17, 2012·Journal of Voice : Official Journal of the Voice Foundation·Mike SheuMilan R Amin
Mar 20, 2014·The Annals of Otology, Rhinology, and Laryngology·Petros D KarkosCosta Repanos
Jan 27, 2015·Journal of Voice : Official Journal of the Voice Foundation·Mark A FritzMilan R Amin
Mar 22, 2015·Journal of Voice : Official Journal of the Voice Foundation·Marco A Mascarella, Jonathan Young
Jan 28, 2017·Journal of Gastroenterology and Hepatology·Riley BatchelorDanny Liew

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

ImageJ

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Voice : Official Journal of the Voice Foundation
Rachel E ArffaClark A Rosen
The Annals of Otology, Rhinology, and Laryngology
Stephen B ClyneGregory N Postma
© 2022 Meta ULC. All rights reserved