PMID: 11324954Apr 28, 2001Paper

Treatment planning for heavy ion radiotherapy: clinical implementation and application

Physics in Medicine and Biology
O JäkelJ Debus

Abstract

The clinical implementation and application of a novel treatment planning system (TPS) for scanned ion beams is described, which is in clinical use for carbon ion treatments at the German heavy ion facility (GSI). All treatment plans are evaluated on the basis of biologically effective dose distributions. For therapy control, in-beam positron emission tomography (PET) and an online monitoring system for the beam intensity and position are used. The absence of a gantry restricts the treatment plans to horizontal beams. Most of the treatment plans consist of two nearly opposing lateral fields or sometimes orthogonal fields. In only a very few cases a single beam was used. For patients with very complex target volumes lateral and even distal field patching techniques were applied. Additional improvements can be achieved when the patient's head is fixed in a tilted position, in order to achieve sparing of the organs at risk. In order to test the stability of dose distributions in the case of patient misalignments we routinely simulate the effects of misalignments for patients with critical structures next to the target volume. The uncertainties in the range calculation are taken into account by a margin around the target volume of ...Continue Reading

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Citations

Jan 31, 2004·International Journal of Radiation Oncology, Biology, Physics·Daniela Schulz-ErtnerJürgen Debus
Sep 21, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Daniela Schulz-ErtnerJürgen Debus
May 15, 2002·International Journal of Radiation Oncology, Biology, Physics·Daniela Schulz-ErtnerJürgen Debus
May 10, 2003·International Journal of Radiation Oncology, Biology, Physics·Daniela Schulz-ErtnerJürgen Debus
Mar 20, 2008·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Michael Krämer, Oliver Jäkel
Oct 16, 2009·Radiation Protection Dosimetry·Oliver Jäkel
May 6, 2004·Medical Physics·Hansjörg Wertz, Oliver Jäkel
Oct 16, 2008·Radiation Oncology·Sven Oliver GrözingerEike Rietzel
Nov 7, 2012·Medical Physics·Hermann FuchsDietmar Georg
Jul 8, 2014·International Journal of Radiation Oncology, Biology, Physics·Maria SaagerChristian P Karger
Dec 6, 2014·Radiation Oncology·Filippo AmmazzalorsoWolfgang Schlegel
Nov 30, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Stephanie E CombsJürgen Debus
Jul 20, 2010·International Journal of Radiation Oncology, Biology, Physics·Ingmar SchlamppDaniela Schulz-Ertner
Jul 23, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Maria SaagerChristian P Karger
Mar 17, 2007·International Journal of Radiation Oncology, Biology, Physics·Daniela Schulz-ErtnerJürgen Debus
Oct 24, 2006·International Journal of Radiation Oncology, Biology, Physics·Daniela Schulz-ErtnerJürgen Debus
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Jul 15, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Alexandra D JensenJürgen Debus
Aug 18, 2009·Biochimica Et Biophysica Acta·Emmanouil FokasRita Engenhart-Cabillic
Apr 18, 2015·Radiation Oncology·Antoni RucinskiOliver Jäkel
Nov 26, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Christopher M RankSteffen Greilich
Jul 11, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Silvia MolinelliPiero Fossati
Oct 8, 2003·Technology in Cancer Research & Treatment·O JäkelJ Debus
Oct 8, 2003·Technology in Cancer Research & Treatment·M KrämerM Scholz
Aug 5, 2003·Physics in Medicine and Biology·M KrämerW Weyrather
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Sep 11, 2004·Physics in Medicine and Biology·Qiang LiGerhard Kraft
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Nov 18, 2006·Physics in Medicine and Biology·Igor PshenichnovWalter Greiner
Jan 18, 2007·Physics in Medicine and Biology·Oliver Jäkel, Petra Reiss
Nov 22, 2007·Physics in Medicine and Biology·Paulo CrespoAndreas Wagner
May 23, 2008·Physics in Medicine and Biology·Nobuyuki KanematsuMasami Torikoshi
May 23, 2008·Physics in Medicine and Biology·Philip M Evans

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