Treatment Principle Based on the Clinical Staging of Pharyngocutaneous Fistula

International Journal of Otolaryngology
Wei SunXiao-Lin Zhu

Abstract

Studies on factors affecting pharyngocutaneous fistulas (PCFs) and PCF repair methods have been widely reported. However, the healing phases of PCF are unclear, and their elucidation could guide clinical treatment. Clinical stages of the PCF healing process were identified by a retrospective study of 39 patients with head and neck cancer who developed a PCF. Different conservative treatments were performed in turn according to three defined stages of the PCF healing process: stage I (drainage and debriding period), stage II (pressure dressing period), and stage III (healing period). A 7-day course of antibiotic therapy was only performed in stage I in 23 patients. The PCF was cured in 30 (76.9%) of 39 patients; the remaining 9 patients underwent subsequent surgical interventions for PCF healing. The three stages of PCF healing have a certain reference value in guiding clinical treatments. Moreover, antibiotics should be used in stage I when signs of infection are present, but they should not be used in all three phases of conservative treatment.

References

Apr 5, 2002·Plastic and Reconstructive Surgery·David W ChangGregory P Reece
Sep 30, 2003·Current Opinion in Otolaryngology & Head and Neck Surgery·Antti A MäkitiePatrick J Gullane
Feb 26, 2005·Plastic and Reconstructive Surgery·Karen W E SngCarlos R Barcelo
Nov 9, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jacopo GalliGaetano Paludetti
Oct 6, 2006·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Antti A MäkitieTimo Atula
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
May 17, 2014·Brazilian Journal of Otorhinolaryngology·Suzana Boltes CecattoCarla Isabel Ferreira Pinto Moura
Sep 24, 2014·American Journal of Otolaryngology·Eleni M BensonRay G F Blanco
Dec 3, 2014·European Annals of Otorhinolaryngology, Head and Neck Diseases·E LoaecR Marianowski
May 13, 2015·American Journal of Otolaryngology·Thunchai Thanasumpun, Pete S Batra
Feb 24, 2016·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·M BusoniO Gallo

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