PMID: 8589001Nov 1, 1995Paper

Treatment results of Hodgkin's disease in Indian children

Pediatric Hematology and Oncology
G KapoorS K Pai

Abstract

This is a retrospective study of Hodgkin's disease in children less than 15 years of age who were registered at Tata Memorial Hospital in India from January 1985 through December 1990. Clinicopathologic characteristics and response were evaluated in 147 patients and survival was calculated in 187. There were 126 boys and 21 girls (6:1). All patients were treated with combination chemotherapy and involved field radiotherapy. The COPP schedule was given to 108 patients. COPP/ABVD to 33, and ABVD to 6. Ninety-three patients (63%) had stage I or II disease and 54 (37%) had stage III or IV disease. B symptoms were observed in 65 patients (56%) and bulky disease in 40 (27%). Histologically, the most common subtype was mixed cellularity, seen in 95 patients (65%). Complete response was observed in 136 (89%), partial response in 6 (4%), and there were 4 treatment-related deaths. Relapse has been observed in 11%. Seven-year actuarial survival was 73% and event-free survival was 64%. Median survival has not yet been reached, with a median follow-up of 36 months.

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Citations

Jan 7, 2010·Journal of Pediatric Hematology/oncology·Zehra FadooAhmed Naqvi
Oct 18, 2012·Journal of Pediatric Hematology/oncology·Amita TrehanRadhika Srinivasan
Jan 1, 1997·Leukemia & Lymphoma·M V PreciadoS Grinstein
Nov 23, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Veronique DinandRajvir Singh
Mar 31, 2017·Indian Journal of Pediatrics·Venkatraman RadhakrishnanSameer Bakhshi
Jul 19, 2008·Pediatric Blood & Cancer·Jagdish ChandraHarish Pemde
Sep 15, 2005·Pediatric Blood & Cancer·Laxman S AryaTribhuvan S Vats
Nov 3, 2017·Journal of Global Oncology·Venkatraman RadhakrishnanTenali Gnana Sagar

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