Abstract
Sixty-two previously untreated patients with squamous cell carcinoma of the base of tongue were retrospectively analyzed. The American Joint Committee on Cancer (AJCC) Stage distribution was I-3, II-7, III-24, and IV-28. The choice of treatment was nonrandomized. The local control was 10/18 with high-dose preoperative radiation, 17/30 with external beam radiation only, and 4/14 with external beam plus interstitial implantation. The median survival for the three treatment regimens were 63, 51, and 13 months, respectively. Preoperative radiation is suggested for tumors with inferior (laryngeal) spread or those with extensive superior extension (to tonsillar fossa and beyond). For centrally placed lesions in the base of the tongue (with or without lateral hypopharyngeal wall spread), radiation alone is recommended. An interstitial implantation should be restricted to lesions equal to or less than 4 x 3 x 2.5 cm3. Since this insertion is technically more demanding than for tumors of the mobile tongue, they should be performed by the more experienced brachytherapist.
References
Jan 1, 1986·International Journal of Radiation Oncology, Biology, Physics·A J Gray
Jan 1, 1987·International Journal of Radiation Oncology, Biology, Physics·V A MarcialJ Stetz
Apr 1, 1987·International Journal of Radiation Oncology, Biology, Physics·K E GardnerN J Cassisi
Apr 1, 1987·International Journal of Radiation Oncology, Biology, Physics·M HoussetL Miglianico
Oct 1, 1986·Radiology·R B LufkinW N Hanafee
Dec 1, 1986·Journal of Surgical Oncology·B L HintzM Wollin
Feb 1, 1987·Clinical Otolaryngology and Allied Sciences·S G LarssonG J Juillard
May 1, 1985·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S G TaylorD D Caldarelli
May 1, 1985·Cancer·C C WangH D Suit
Mar 1, 1985·Cancer·D R GoffinetR L Goode
Feb 1, 1985·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·W Van den BogaertV Svoboda
Aug 1, 1985·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R KneeL J Peters
Oct 1, 1985·International Journal of Radiation Oncology, Biology, Physics·B VikramB Hilaris
Dec 1, 1985·American Journal of Clinical Oncology·C C Wang
Nov 1, 1984·International Journal of Radiation Oncology, Biology, Physics·J T ParsonsR R Million
Jun 1, 1984·International Journal of Radiation Oncology, Biology, Physics·R T MeozH D Thames
Mar 1, 1983·International Journal of Radiation Oncology, Biology, Physics·T D NguyenD Froissart
Jan 1, 1981·International Journal of Radiation Oncology, Biology, Physics·G Peracchia, C Salti
May 1, 1980·International Journal of Radiation Oncology, Biology, Physics·J T FazekasS Kramer
Citations
Sep 1, 1997·Head & Neck·M MachtayG Weinstein
Jun 1, 2010·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Jaimanti BakshiVikas I Nehru
Jan 15, 1996·International Journal of Radiation Oncology, Biology, Physics·D A FeinR R Million
Aug 12, 2003·International Journal of Radiation Oncology, Biology, Physics·Yoichiro HosokawaMotoyasu Nakamura
Oct 1, 1990·American Journal of Surgery·R S WeberO Guillamondegui
Oct 18, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R M TiwariG B Snow
Jul 3, 2003·The Laryngoscope·Donald G SessionsOmer Ahmad Chaudry
Apr 6, 2004·Surgical Oncology Clinics of North America·Ryan F Osborne, Jimmy J Brown