PMID: 16509460Mar 3, 2006Paper

Treatment with antidepressive drugs improved quality of life in chronic hemodialysis patients

Clinical Nephrology
S TurkA Yildiz

Abstract

Despite some improvements in dialysis therapies, depression still remains an important problem in chronic hemodialysis (HD) patients. In this study, we aimed to investigate the association of depression and its treatment with quality of life (QOL) in HD patients. 97 HD patients (52 male, 45 female, mean age 55 +/- 16 years) were enrolled. All patients had been dialyzed for more than 6 months. In order to evaluate QOL of the patients, a short form of Medical Outcomes Study (SF-36) was used. Depression was assessed by using Beck Depression Inventory (BDI). Patients who had BDI score > or = 15 were diagnosed as to have depression. Patients with depression received antidepressive treatment (sertralin HCl, 50 mg/day) for an 8-week period. After 8-week antidepressive treatment, all biochemical analysis, SF-36 and BDI were performed again. 40 patients (20 male, 20 female, mean age 56 +/- 14 years) had depression. All parameters related to QOL were significantly decreased in patients with depression as compared to patients without depression. Severity of depression was correlated with QOL parameters. After 8 weeks of treatment, as parallel to changes in BDI, QOL parameters improved in patients with depression. Decrease in QOL, associat...Continue Reading

Citations

Oct 26, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Aaron S YarlasTorsten Christensen
May 12, 2009·International Urology and Nephrology·Baris AfsarNurhan F Ozdemir
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Jun 22, 2010·Scandinavian Journal of Occupational Therapy·Milton Carlos Mariotti, José Gastão Rocha de
Oct 22, 2009·The International Journal of Artificial Organs·Fabrizio FabriziPaul Martin
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Jul 14, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S Susan Hedayati, Fredric O Finkelstein

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