Trefoil Factor Family: Unresolved Questions and Clinical Perspectives.

Trends in Biochemical Sciences
Nayara Braga EmidioMarkus Muttenthaler

Abstract

The trefoil factor family of peptides (TFF1, TFF2, TFF3) with their lectin activities play important roles in mucosal protection and repair. However, major gaps in understanding their molecular function have hampered therapeutic development for gastrointestinal disorders. We provide here a critical overview of the status quo.

Citations

Oct 30, 2019·International Journal of Molecular Sciences·Till HoubenWerner Hoffmann
May 12, 2020·Chemical Communications : Chem Comm·Nayara Braga EmidioMarkus Muttenthaler
Aug 14, 2019·International Journal of Molecular Sciences·Ghalia KhoderSherif M Karam
May 15, 2020·Nature Communications·Michael A JärvåEthan D Goddard-Borger
Nov 28, 2019·International Journal of Molecular Sciences·Franziska HeuerWerner Hoffmann
Sep 26, 2020·Translational Vision Science & Technology·Anne M LynchNaresh Mandava
Sep 5, 2019·International Journal of Molecular Sciences·Katharina KrügerKolja Gelse
Jan 23, 2020·International Journal of Molecular Sciences·Eva B ZnalesniakWerner Hoffmann
Jan 29, 2021·World Journal of Gastroenterology : WJG·Yun HuangShi-Nan Nie
Aug 25, 2020·ACS Pharmacology & Translational Science·Nayara Braga EmidioMarkus Muttenthaler
Jun 20, 2021·The Journal of Biological Chemistry·Bichen ZhangXiaoyong Yang
Jun 19, 2021·Journal of Medicinal Chemistry·Nayara Braga EmidioMarkus Muttenthaler
Jul 16, 2021·Signal Transduction and Targeted Therapy·Hong-Yong CuiZhi-Nan Chen

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