Trehalose-6-phosphate signaling regulates thermoresponsive hypocotyl growth in Arabidopsis thaliana

EMBO Reports
Geonhee HwangEunkyoo Oh

Abstract

Growth plasticity is a key mechanism by which plants adapt to the ever-changing environmental conditions. Since growth is a high-energy-demanding and irreversible process, it is expected to be regulated by the integration of endogenous energy status as well as environmental conditions. Here, we show that trehalose-6-phosphate (T6P) functions as a sugar signaling molecule that coordinates thermoresponsive hypocotyl growth with endogenous sugar availability. We found that the loss of T6P SYNTHASE 1 (TPS1) in Arabidopsis thaliana impaired high-temperature-mediated hypocotyl growth. Consistently, the activity of PIF4, a transcription factor that positively regulates hypocotyl growth, was compromised in the tps1 mutant. We further show that, in the tps1 mutant, a sugar signaling kinase KIN10 directly phosphorylates and destabilizes PIF4. T6P inhibits KIN10 activity in a GRIK-dependent manner, allowing PIF4 to promote hypocotyl growth at high temperatures. Together, our results demonstrate that T6P determines thermoresponsive growth through the KIN10-PIF4 signaling module. Such regulation of PIF4 by T6P integrates the temperature-signaling pathway with the endogenous sugar status, thus optimizing plant growth response to environmenta...Continue Reading

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Citations

Jan 26, 2021·Plant Science : an International Journal of Experimental Plant Biology·Hang ZhaoGang Li
Feb 16, 2021·Trends in Plant Science·Young-Joon ParkChung-Mo Park
Feb 6, 2021·Journal of Experimental Botany·Johanna KrahmerKaren J Halliday
Mar 12, 2021·Journal of Experimental Botany·Muhammed Jamsheer KVibha Srivastava
May 12, 2021·Journal of Experimental Botany·Martijn van ZantenMarcel Quint
Jun 23, 2021·Communications Biology·Gilor KellyDavid Granot
Jun 18, 2021·Science Advances·Rafael CataláJulio Salinas
Sep 5, 2021·Physiologia Plantarum·Bhuwaneshwar Sharan MishraAshverya Laxmi
Aug 6, 2021·Annual Review of Cell and Developmental Biology·Lei LiJen Sheen
Dec 9, 2020·Developmental Cell·Heng ZhangJian-Kang Zhu

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