PMID: 5892589Dec 1, 1965

Trehalose as an endogenous reserve in spores of the fungus Myrothecium verrucaria

Journal of Bacteriology
G R MandelsF W Parrish


Mandels, G. R. (U.S. Army Natick Laboratories, Natick, Mass.), Rasma Vitols, and Frederick W. Parrish. Trehalose as an endogenous reserve in spores of the fungus Myrothecium verrucaria. J. Bacteriol. 90:1589-1598. 1965.-Gross analysis of Myrothecium verrucaria spores showed approximately 3% fat, 33% carbohydrate, and 9.5% nitrogen. The water-soluble carbohydrates were trehalose, glucose, mannitol, and an unidentified phosphorylated compound. Water-soluble amino acids include leucine or norleucine (or both), valine, gamma-amino-n-butyric acid, beta-amino-n-butyric acid, ergothionine, glutamic acid, glutamine, glycine, aspartic acid, asparagine, cystine, and cystathionine. Ergosterol was also present. alphaalpha-Trehalose is the major reserve (20% of the dry weight), although approximately 30% of it appeared to be at the spore surface and was released by nonlethal treatment with 0.1 n HCl. Treatment with toluene or exposure to heat sufficient to kill the spores (20 min at 60 C) caused rapid liberation of all of the trehalose. Although spores could utilize exogenous trehalose with no appreciable lag, some stimulus, such as exposure to heat (10 min at 55 C), incubation with azide, or germination on exogenous substrates, was necessa...Continue Reading


Dec 1, 1972·Planta·J A Van AsscheH I Dekeersmaeker

Related Concepts

Hydrogen Chloride
Reproduction Spores

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.