Trema micrantha toxicity in horses in Brazil

Equine Veterinary Journal
P M BandarraD Driemeier

Abstract

After ingesting green leaves of T. micrantha, 2 horses showed apathy, locomotor deficit, blindness, recumbency, paddling, coma and death. The main gross findings were scattered haemorrhages, enhanced lobular pattern of the liver, and cerebral oedema. Histological changes included disseminated haemorrhages, massive hepatocellular necrosis, neuronal degeneration, Alzheimer type II astrocytes and cerebral perivascular oedema. Clinicopathological findings which were comparable with those observed in Trema micrantha poisoned ruminants, associated with epidemiological evidence suggested the diagnosis.Trema micrantha poisoning should be evaluated as a possible cause in the diagnosis of equine hepatopathy and occasional secondary encephalopathy.

References

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Dec 24, 2008·Metabolic Brain Disease·M D NorenbergA R Jayakumar

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Citations

Feb 19, 2013·Veterinary Pathology·F WoutersD Driemeier
Aug 15, 2017·Equine Veterinary Journal·M P LorenzettD Driemeier
Jul 23, 2019·Toxicon : Official Journal of the International Society on Toxinology·Mizael MachadoMárcio Botelho de Castro

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