Trematode Fluke Procerovum varium as Cause of Ocular Inflammation in Children, South India

Emerging Infectious Diseases
Lalan Kumar AryaV Tandon

Abstract

Trematodes are recognized as a group of emerging parasites in tropical countries. We identified a trematode as a cause of ocular granulomas that developed in children who bathed in ponds or rivers in South India. DNA was isolated from patients' surgically excised granulomas and from the trematode cercariae (larvae) released by the snail Melanoides tuberculata in water in which the children bathed. Real-time and conventional PCRs were performed that targeted ribosomal DNA regions spanning the internal transcribed spacer 2 and 28S sequences of this trematode. The PCR-amplified products were subjected to bidirectional sequencing. Analysis of sequences for the granuloma samples and the trematode cercariae showed maximum sequence similarity with Procerovum varium (family Heterophyidae). Our results confirmed the etiology of the ocular infection, implicating snail vectors as environmental risk factors for ocular parasitosis.

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Citations

Jun 11, 2017·The British Journal of Ophthalmology·R M AminA E Radwan
Nov 6, 2018·Japanese Journal of Ophthalmology·Rowayda Mohamed AminAhmed R H Ahmed
Jan 24, 2020·Acta Ophthalmologica·Sherin Hassan SadekMaha Mohamed Youssef
Sep 19, 2018·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Syed Shoeb Ahmad
Feb 21, 2018·Emerging Infectious Diseases·Eduardo A Pulido-MurilloHudson A Pinto
May 21, 2021·Ocular Immunology and Inflammation·Eman El HefnyAmgad El Nokrashy
Jun 3, 2021·Clinical Microbiology Reviews·Sixto M LealPeter H Gilligan

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Datasets Mentioned

BETA
EU826639.1
HM004184.1

Methods Mentioned

BETA
PCR
electrophoresis
light microscopy

Software Mentioned

BLAST

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