Trends in benzodiazepine receptor agonists use and associated factors in the Belgian general older population: analysis of the Belgian health interview survey data.

Therapeutic Advances in Psychopharmacology
Catherine PéteinSéverine Henrard

Abstract

Benzodiazepine receptor agonists (BZRA), which include benzodiazepines and z-drugs, are commonly prescribed for insomnia and anxiety in older adults, and used often long term. Yet, the risk-benefit ratio of BZRA use in older adults may be unfavorable and many recommendations suggest avoidance or a maximal treatment duration of 4 weeks. The aim of this study was to describe trends of BZRA use in older adults and associated factors. Using data from the Belgian Health Interview Survey in 2004 (n = 3594), 2008 (n = 2917), and 2013 (n = 2048), prevalence standardized for age, sex, and region were calculated to assess trends of BZRA use in people ⩾65 years. Analysis of associated factors to BZRA use was performed using a sub-sample of 2013 data for which variables assessing sleeping disorder and anxiety disorder were not missing (n = 1286). Variables from seven main topics were explored using multivariate logistic regression: socio-demographic factors, geriatric factors, comorbidities, subjective health and mental health indicators, social health indicators, medication use and healthcare services use. Overall, standardized prevalence of BZRA use decreased significantly between 2004 and 2013 [22% to 18%, prevalence difference (95% con...Continue Reading

References

Nov 17, 1998·Journal of Clinical Epidemiology·A LeplègeT V Perneger
Jan 6, 2000·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·M H Lader
Aug 13, 2005·Bioinformatics·Tobias SingThomas Lengauer
Dec 7, 2007·International Journal of Geriatric Psychiatry·Jur-Shan ChengYaw-Tang Shih
Oct 25, 2008·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Borwin BandelowJohann Vega
Mar 17, 2010·Annals of Internal Medicine·Patrick HaentjensSteven Boonen
Sep 25, 2010·Journal of the American Geriatrics Society·David BuckeridgeRobyn Tamblyn
Jan 25, 2011·Pharmacoepidemiology and Drug Safety·Ane Birgitte Telén Andersen, Morten Frydenberg
Apr 12, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M HerdmanX Badia
Dec 23, 2011·European Journal of Clinical Pharmacology·Jolyce BourgeoisRobert R Vander Stichele
Jun 19, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Thibault MuraClaudine Berr
Oct 17, 2012·International Psychogeriatrics·P Carrasco-GarridoR Jiménez-García
Sep 21, 2013·Archives of public health = Archives belges de santé publique·Stefaan DemarestJean Tafforeau
Sep 27, 2013·Journal of Psychopharmacology·David S BaldwinSue Wilson
Dec 9, 2014·CMAJ Open·Silvia Alessi-SeveriniJitender Sareen
Dec 18, 2014·JAMA Psychiatry·Mark OlfsonMichael Schoenbaum
Jul 5, 2015·BMC Pharmacology & Toxicology·André S PollmannDavid M Gardner
Nov 7, 2015·European Psychiatry : the Journal of the Association of European Psychiatrists·T A T KurkoJ Hietala
Nov 12, 2015·Archives of public health = Archives belges de santé publique·Denise WalckiersJean Tafforeau
Apr 14, 2016·The Annals of Pharmacotherapy·Zachary A MarcumUNKNOWN Health ABC Study
Apr 27, 2016·International Journal of Geriatric Psychiatry·Kristina JohnellPeter Salmi
Nov 24, 2016·Journal of the American Geriatrics Society·Donovan T MaustMark Olfson
May 1, 2017·European Journal of Clinical Pharmacology·Emily ReeveDanijela Gnjidic
May 26, 2017·Maturitas·Mª José Díaz-GutiérrezAna González-Pinto
Jul 26, 2017·Therapeutic Advances in Psychopharmacology·Louis JacobKarel Kostev
Mar 2, 2018·Therapeutic Advances in Psychopharmacology·Simon J C DaviesPaul Kurdyak
Sep 13, 2018·JAMA Internal Medicine·Lauren B GerlachDavid W Oslin
Jan 30, 2019·Journal of the American Geriatrics Society·UNKNOWN By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel
Nov 17, 2019·European Journal of Clinical Pharmacology·Stephanie HeinemannWolfgang Himmel
Aug 14, 2020·Journal of the American Geriatrics Society·Perrine EvrardAnne Spinewine

❮ Previous
Next ❯

Software Mentioned

questionr
car
ResourceSelection
ROCR
dsr
R

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.