Trends in contact lens microbial keratitis 1999 to 2015: a retrospective clinical review

Clinical & Experimental Ophthalmology
Matthew GreenFiona Stapleton

Abstract

Contact lens microbial keratitis (CLMK) is the most common cause of microbial keratitis in our community. Define the trend in rate of CLMK and define patient demographics/culture results that may have a predictive value in patients with CLMK. Retrospective review of clinical records of patients with MK. All patients with positive corneal scraping between 1999 and 2015 at the Princess Alexandra Hospital, Brisbane, Queensland identified through local microbiology database. Trend in CLMK tested with chi-squared test of peak 3 years vs other years and Poisson regression of interrupted time series. Patient characteristics predictive of CLMK were defined by creating a polynomial regression model by stepwise variable selection. Yearly rate of CLMK. Records of 895 episodes of MK were included. The most common: risk factor was contact lens wear (324, 36.2%), isolated organism was Pseudomonas aeruginosa (P. aeruginosa 181, 55.9%) and treatment was monotherapy with a fluoroquinolone 172, 53%). CLMK was most common between 2009 and 2011 (49.5% vs other years 32%, P < 0.001). Poisson regression of the interrupted time series showed there was a significant decrease in the rate over time after 2010 (P < 0.001). Independent factors predictive ...Continue Reading

References

Aug 21, 2003·The British Journal of Ophthalmology·T WongC N J McGhee
Dec 20, 2005·Ophthalmology·Lisa KeayFiona Stapleton
Jul 27, 2007·Clinical & Experimental Ophthalmology·Matthew D GreenFiona J Stapleton
Feb 5, 2008·Cornea·Matthew GreenFiona Stapleton
Jun 10, 2008·Ophthalmology·Fiona StapletonBrien A Holden
Sep 3, 2009·Clinical & Experimental Ophthalmology·Jae Yee KuPeter Beckingsale
Dec 20, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Nathan EfronUNKNOWN International Contact Lens Prescribing Survey Consortium
Aug 3, 2012·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Nathan EfronUNKNOWN International Contact Lens Prescribing Survey Consortium
Jan 12, 2013·JAMA Ophthalmology·Kathryn J RayThomas M Lietman

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Citations

Dec 7, 2019·Biomedizinische Technik. Biomedical Engineering·Katharina HoenesMartin Hessling
May 5, 2020·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Fiona Stapleton
Apr 2, 2021·Clinical Ophthalmology·Chantaka Supiyaphun, Passara Jongkhajornpong
May 29, 2020·ACS Applied Materials & Interfaces·Carolin A RickertOliver Lieleg

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